Immunohistochemistry (IHC)
(Anti-AQP1 / Aquaporin 1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
Rabbit anti-Human, Mouse AQP1 / Aquaporin 1 Polyclonal Antibody | anti-AQP1 antibody
Rabbit Polyclonal to Human AQP1 / Aquaporin 1
Immunohistochemistry (IHC)
(Anti-AQP1 / Aquaporin 1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
Immunohistochemistry (IHC)
(Anti-AQP1 / Aquaporin 1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
Western Blot (WB)
(AQP1 Antibody (C-term) Western blot of mouse brain tissue lysates (35 ug/lane). This demonstrates the AQP1 antibody detected the AQP1 protein (arrow).)
Western Blot (WB)
(AQP1 Antibody (C-term) Western blot of mouse brain tissue lysates (35 ug/lane). This demonstrates the AQP1 antibody detected the AQP1 protein (arrow).)
Western Blot (WB)
(AQP1 Antibody (C-term) Western blot of A549 cell line lysates (35 ug/lane). This demonstrates the AQP1 antibody detected the AQP1 protein (arrow).)
Western Blot (WB)
(AQP1 Antibody (C-term) Western blot of A549 cell line lysates (35 ug/lane). This demonstrates the AQP1 antibody detected the AQP1 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Uniprot Description
AQP1: Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, aquaporin family
Chromosomal Location of Human Ortholog: 7p14
Cellular Component: nuclear membrane; brush border membrane; basolateral plasma membrane; apical part of cell; integral to plasma membrane; cytoplasm; apical plasma membrane; basal plasma membrane; plasma membrane; nerve terminal; nucleus; sarcolemma; brush border
Molecular Function: protein binding; ephrin receptor binding; potassium channel activity; water transporter activity; ammonium transmembrane transporter activity; intracellular cGMP activated cation channel activity; potassium ion transmembrane transporter activity; glycerol transmembrane transporter activity; nitric oxide transporter activity; transmembrane transporter activity; water channel activity; glycerol channel activity
Biological Process: cGMP biosynthetic process; glycerol transport; cerebrospinal fluid secretion; wound healing; water transport; carbon dioxide transport; cellular response to stress; negative regulation of caspase activity; pancreatic juice secretion; sensory perception of pain; positive regulation of saliva secretion; odontogenesis; positive regulation of fibroblast proliferation; nitric oxide transport; hyperosmotic salinity response; bicarbonate transport; cellular homeostasis; multicellular organismal water homeostasis; transmembrane transport; lateral ventricle development; lipid digestion; potassium ion transport; response to drug; cellular water homeostasis; secretory granule organization and biogenesis; glomerular filtration; ammonium transport; positive regulation of angiogenesis; renal water transport; camera-type eye morphogenesis; response to estrogen stimulus; adrenocorticotropin hormone secretion; establishment and/or maintenance of actin cytoskeleton polarity; renal water homeostasis; cell volume homeostasis; negative regulation of apoptosis
Disease: Blood Group--colton
Research Articles on AQP1
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Product Notes
The AQP1 aqp1 (Catalog #AAA247992) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human AQP1 / Aquaporin 1 reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AQP1 / Aquaporin 1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (1:100), WB (1:1000). Researchers should empirically determine the suitability of the AQP1 aqp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AQP1 / Aquaporin 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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