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Immunohistochemistry (IHC) (Anti-INPP5J / PIB5PA antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit INPP5J / PIB5PA Polyclonal Antibody | anti-INPP5J antibody

Rabbit Polyclonal to Human INPP5J / PIB5PA

Gene Names
INPP5J; PIPP; INPP5; PIB5PA
Reactivity
Bat, Gibbon, Bovine, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
INPP5J / PIB5PA; Polyclonal Antibody; Rabbit Polyclonal to Human INPP5J / PIB5PA; Anti-INPP5J / PIB5PA Antibody (C-Terminus) IHC-plus; INPP5J; PIB5PA; INPP5; PIPP; Human INPP5J; anti-INPP5J antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Bat, Gibbon, Bovine, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Clonality
Polyclonal
Specificity
Human INPP5J / PIB5PA. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PPP1R3A (50%).
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
638
Applicable Applications for anti-INPP5J antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (6 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 18 amino acid peptide from near C-terminus of human INPP5J / PIB5PA.
Immunogen Type
Synthetic peptide
Immunogen
INPP5J / PIB5PA antibody was raised against synthetic 18 amino acid peptide from near C-terminus of human INPP5J / PIB5PA. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit, Pig (100%); Platypus (83%).
Antigen Modification
C-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-INPP5J / PIB5PA antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-INPP5J / PIB5PA antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Product Categories/Family for anti-INPP5J antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
70,239 Da
NCBI Official Full Name
phosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform c
NCBI Official Synonym Full Names
inositol polyphosphate-5-phosphatase J
NCBI Official Symbol
INPP5J
NCBI Official Synonym Symbols
PIPP; INPP5; PIB5PA
NCBI Protein Information
phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; inositol polyphosphate 5-phosphatase J; phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A
UniProt Protein Name
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
UniProt Gene Name
INPP5J
UniProt Synonym Gene Names
PIB5PA; PIPP
UniProt Entry Name
PI5PA_HUMAN

Uniprot Description

PI5PA: Inositol 5-phosphatase, which converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4- phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate- binding proteins that are present at membranes ruffles. Belongs to the inositol 1,4,5-trisphosphate 5- phosphatase type II family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - inositol phosphate; Phosphatase (non-protein); EC 3.1.3.56

Chromosomal Location of Human Ortholog: 22q12.2

Cellular Component: ruffle; growth cone; cytoplasm; plasma membrane; dendritic shaft; cytosol

Molecular Function: inositol-polyphosphate 5-phosphatase activity; SH3 domain binding

Biological Process: inositol phosphate metabolic process; negative regulation of microtubule polymerization; phospholipid metabolic process; negative regulation of peptidyl-serine phosphorylation; phosphatidylinositol biosynthetic process; phosphoinositide dephosphorylation

Research Articles on INPP5J

Similar Products

Product Notes

The INPP5J inpp5j (Catalog #AAA247905) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human INPP5J / PIB5PA reacts with Bat, Gibbon, Bovine, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's INPP5J / PIB5PA can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (6 ug/ml). Researchers should empirically determine the suitability of the INPP5J inpp5j for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "INPP5J / PIB5PA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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