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Immunohistochemistry (IHC) (Anti-NMBR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit NMBR Polyclonal Antibody | anti-NMBR antibody

Rabbit Polyclonal to Human NMBR

Gene Names
NMBR; BB1
Reactivity
Gibbon, Gorilla, Human
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
NMBR; Polyclonal Antibody; Rabbit Polyclonal to Human NMBR; Anti-NMBR Antibody (C-Terminus) IHC-plus; Bombesin BB1 receptor; Neuromedin-B receptor; Neuromedin B receptor; NMB-preferring receptor; NMB-R; Human NMBR; anti-NMBR antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Gibbon, Gorilla, Human
Clonality
Polyclonal
Specificity
Human NMBR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
390
Applicable Applications for anti-NMBR antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (9 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 19 amino acid peptide from C-terminus of human NMBR. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset, Mouse, Elephant, Bovine (89%); Rat, Panda, Dog, Bat, Rabbit, Pig, Platypus (84%).
Immunogen Type
Synthetic peptide
Immunogen
NMBR antibody was raised against synthetic 19 amino acid peptide from C-terminus of human NMBR. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset, Mouse, Elephant, Bovine (89%); Rat, Panda, Dog, Bat, Rabbit, Pig, Platypus (84%).
Antigen Modification
C-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-NMBR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-NMBR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-NMBR antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-NMBR antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-NMBR antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-NMBR antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-NMBR antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-NMBR antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-NMBR antibody
The neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues.
Product Categories/Family for anti-NMBR antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
43,435 Da
NCBI Official Full Name
neuromedin-B receptor
NCBI Official Synonym Full Names
neuromedin B receptor
NCBI Official Symbol
NMBR
NCBI Official Synonym Symbols
BB1
NCBI Protein Information
neuromedin-B receptor; NMB-R; bombesin receptor 1; epididymis tissue protein Li 185a; neuromedin-B-preferring bombesin receptor
UniProt Protein Name
Neuromedin-B receptor
Protein Family
UniProt Gene Name
NMBR
UniProt Synonym Gene Names
NMB-R
UniProt Entry Name
NMBR_HUMAN

NCBI Description

Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue. [provided by RefSeq, Jul 2008]

Uniprot Description

NMBR: Receptor for neuromedin-B. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6q24.1

Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane

Molecular Function: bombesin receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; bombesin receptor signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)

Research Articles on NMBR

Similar Products

Product Notes

The NMBR nmbr (Catalog #AAA247080) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human NMBR reacts with Gibbon, Gorilla, Human and may cross-react with other species as described in the data sheet. AAA Biotech's NMBR can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (9 ug/ml). Researchers should empirically determine the suitability of the NMBR nmbr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NMBR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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