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Immunohistochemistry (IHC) (Anti-MEOX2 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Mouse GAX / MEOX2 Monoclonal Antibody | anti-GAX antibody

Mouse Monoclonal [clone 6A5] (IgG1,k) to Human GAX / MEOX2

Gene Names
MEOX2; GAX; MOX2
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
Purity
Protein A Purified
Synonyms
GAX / MEOX2; Monoclonal Antibody; Mouse Monoclonal [clone 6A5] (IgG1; k) to Human GAX / MEOX2; Anti-GAX / MEOX2 Antibody (clone 6A5) IHC-plus; MEOX2; MOX2; Mesenchyme homeobox 2; GAX; Homeobox protein MOX-2; Human GAX; anti-GAX antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
6A5
Specificity
Human Homeobox Protein Mox-2
Purity/Purification
Protein A Purified
Form/Format
PBS, pH 7.4.
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
304
Applicable Applications for anti-GAX antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA, IF (10 ug/ml), IHC-P (5 ug/ml), WB (1:500 - 1:1000)
Usage: Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western blot using cell lysates and the recombinant protein used as the immunogen.
Target Species
Human
Immunogen Description
MEOX2 (AAH17021, 1 a.a. ~ 304 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen
GAX / MEOX2 antibody was raised against mEOX2 (AAH17021, 1 a.a. ~ 304 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.

Immunohistochemistry (IHC)

(Anti-MEOX2 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-MEOX2 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of monoclonal antibody to MEOX2 on HeLa cell. [antibody concentration 10 ug/ml])

Immunofluorescence (IF) (Immunofluorescence of monoclonal antibody to MEOX2 on HeLa cell. [antibody concentration 10 ug/ml])

Western Blot (WB)

(MEOX2 monoclonal antibody clone 6A5. Western blot of MEOX2 expression in PC-12.)

Western Blot (WB) (MEOX2 monoclonal antibody clone 6A5. Western blot of MEOX2 expression in PC-12.)

Western Blot (WB)

(MEOX2 monoclonal antibody clone 6A5. Western blot of MEOX2 expression in NIH/3T3.)

Western Blot (WB) (MEOX2 monoclonal antibody clone 6A5. Western blot of MEOX2 expression in NIH/3T3.)

Western Blot (WB)

(MEOX2 monoclonal antibody clone 6A5 Western blot of MEOX2 expression in HeLa.)

Western Blot (WB) (MEOX2 monoclonal antibody clone 6A5 Western blot of MEOX2 expression in HeLa.)

ELISA (EIA)

(Detection limit for recombinant GST tagged MEOX2 is approximately 0.3 ng/ml as a capture antibody.)

ELISA (EIA) (Detection limit for recombinant GST tagged MEOX2 is approximately 0.3 ng/ml as a capture antibody.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33,594 Da
NCBI Official Full Name
homeobox protein MOX-2
NCBI Official Synonym Full Names
mesenchyme homeobox 2
NCBI Official Symbol
MEOX2
NCBI Official Synonym Symbols
GAX; MOX2
NCBI Protein Information
homeobox protein MOX-2; growth arrest-specific homeobox
UniProt Protein Name
Homeobox protein MOX-2
UniProt Gene Name
MEOX2
UniProt Synonym Gene Names
GAX; MOX2
UniProt Entry Name
MEOX2_HUMAN

NCBI Description

This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. [provided by RefSeq, Jul 2008]

Uniprot Description

MEOX2: Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 7p22.1-p21.3

Cellular Component: cytoplasm; nuclear speck; nucleus

Molecular Function: protein binding; sequence-specific DNA binding; transcription factor activity

Biological Process: limb development; skeletal muscle development; somite specification; transcription, DNA-dependent; blood circulation; multicellular organismal development; positive regulation of transcription from RNA polymerase II promoter; angiogenesis; palate development

Research Articles on GAX

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Product Notes

The GAX meox2 (Catalog #AAA245969) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 6A5] (IgG1,k) to Human GAX / MEOX2 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GAX / MEOX2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA). ELISA, IF (10 ug/ml), IHC-P (5 ug/ml), WB (1:500 - 1:1000) Usage: Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western blot using cell lysates and the recombinant protein used as the immunogen. Researchers should empirically determine the suitability of the GAX meox2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GAX / MEOX2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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