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Immunohistochemistry (IHC) (Anti-DUSP9 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.)

Rabbit DUSP9 Polyclonal Antibody | anti-DUSP9 antibody

Rabbit Polyclonal (IgG) to Human DUSP9

Gene Names
DUSP9; MKP4; MKP-4
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
DUSP9; Polyclonal Antibody; Rabbit Polyclonal (IgG) to Human DUSP9; Anti-DUSP9 Antibody (aa151-200) IHC-plus; Dual specificity phosphatase 9; MAP kinase phosphatase 4; MKP-4; MKP4; DUSP 9; Human DUSP9; anti-DUSP9 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
DUSP9 Antibody detects endogenous levels of total DUSP9 protein.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
384
Applicable Applications for anti-DUSP9 antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA (1:20000), IF (1:100 - 1:500), IHC-P (5 ug/ml), WB (1:500 - 1:1000)
Target Species
Human
Immunogen Description
Synthetic peptide from human DUSP9 (aa151-200).
Immunogen
DUSP9 antibody was raised against synthetic peptide from human DUSP9 (aa151-200).
Antigen Modification
aa151-200
Preparation and Storage
Store at -20 degree C for up to one year.

Immunohistochemistry (IHC)

(Anti-DUSP9 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-DUSP9 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of HeLa cells, using DUSP9 Antibody. The picture on the right is treated with the synthesized peptide.)

Immunofluorescence (IF) (Immunofluorescence of HeLa cells, using DUSP9 Antibody. The picture on the right is treated with the synthesized peptide.)

Western Blot (WB)

(Western blot of extracts from HeLa cells, using DUSP9 Antibody. The lane on the right is treated with the synthesized peptide.)

Western Blot (WB) (Western blot of extracts from HeLa cells, using DUSP9 Antibody. The lane on the right is treated with the synthesized peptide.)
Related Product Information for anti-DUSP9 antibody
DUSP9 encodes a dual specificity MAP kinase phosphatase which has been shown to inactivate members of the ERK family in vitro.
Product Categories/Family for anti-DUSP9 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,868 Da
NCBI Official Full Name
dual specificity protein phosphatase 9
NCBI Official Synonym Full Names
dual specificity phosphatase 9
NCBI Official Symbol
DUSP9
NCBI Official Synonym Symbols
MKP4; MKP-4
NCBI Protein Information
dual specificity protein phosphatase 9; map kinase phosphatase 4; serine/threonine specific protein phosphatase; mitogen-activated protein kinase phosphatase 4
UniProt Protein Name
Dual specificity protein phosphatase 9
UniProt Gene Name
DUSP9
UniProt Synonym Gene Names
MKP4; MAP kinase phosphatase 4; MKP-4
UniProt Entry Name
DUS9_HUMAN

NCBI Description

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus. [provided by RefSeq, Jul 2008]

Uniprot Description

DUSP9: a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (ERK, JNK, p38). Shows selectivity for members of the ERK family, is expressed at high levels in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus.

Protein type: EC 3.1.3.16; Protein phosphatase, dual-specificity; EC 3.1.3.48; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; MAP kinase tyrosine/serine/threonine phosphatase activity; phosphoprotein phosphatase activity

Biological Process: JNK cascade; protein amino acid dephosphorylation; inactivation of MAPK activity

Research Articles on DUSP9

Similar Products

Product Notes

The DUSP9 dusp9 (Catalog #AAA243766) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human DUSP9 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DUSP9 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA). ELISA (1:20000), IF (1:100 - 1:500), IHC-P (5 ug/ml), WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the DUSP9 dusp9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DUSP9, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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