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Immunohistochemistry (IHC) (Anti-PLXNB1 / Plexin B1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Rabbit anti-Human, Mouse PLXNB1 / Plexin-B1 Polyclonal Antibody | anti-PLXNB1 antibody

Rabbit Polyclonal (IgG) to Human PLXNB1 / Plexin-B1

Gene Names
PLXNB1; SEP; PLXN5; PLEXIN-B1
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Protein A Purified
Synonyms
PLXNB1 / Plexin-B1; Polyclonal Antibody; Rabbit Polyclonal (IgG) to Human PLXNB1 / Plexin-B1; Anti-PLXNB1 / Plexin-B1 Antibody IHC-plus; PLXNB1; KIAA0407; Plexin 5; Plexin B1; Semaphorin receptor SEP; PLXN5; SEP; Plexin-B1; Human PLXNB1; anti-PLXNB1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Plexin B1 antibody detects endogenous levels of Plexin B1 protein. Not tested with other proteins.
Purity/Purification
Protein A Purified
Form/Format
PBS, pH 7.4, 0.05% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
2135
Applicable Applications for anti-PLXNB1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA (1:10000), IHC-P (5 ug/ml), WB (1:200)
Target Species
Human
Immunogen Description
Synthetic peptide
Immunogen Type
Synthetic peptide
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.

Immunohistochemistry (IHC)

(Anti-PLXNB1 / Plexin B1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-PLXNB1 / Plexin B1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Western Blot (WB)

( )

Western Blot (WB) ( )

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
78,395 Da
NCBI Official Full Name
plexin-B1
NCBI Official Synonym Full Names
plexin B1
NCBI Official Symbol
PLXNB1
NCBI Official Synonym Symbols
SEP; PLXN5; PLEXIN-B1
NCBI Protein Information
plexin-B1; plexin 5; semaphorin receptor SEP
UniProt Protein Name
Plexin-B1
Protein Family
UniProt Gene Name
PLXNB1
UniProt Synonym Gene Names
KIAA0407; PLXN5; SEP
UniProt Entry Name
PLXB1_HUMAN

Uniprot Description

PLXNB1: Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Belongs to the plexin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, misc.

Chromosomal Location of Human Ortholog: 3p21.31

Cellular Component: integral to plasma membrane; extracellular region; plasma membrane; intracellular

Molecular Function: protein binding; transmembrane receptor activity; semaphorin receptor activity; GTPase activating protein binding; receptor activity; semaphorin receptor binding

Biological Process: positive regulation of phosphoinositide 3-kinase cascade; axon guidance; regulation of cell shape; cell migration; positive regulation of axonogenesis; negative regulation of osteoblast proliferation; negative regulation of cell adhesion; signal transduction; neurite morphogenesis; regulation of cytoskeleton organization and biogenesis

Research Articles on PLXNB1

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Product Notes

The PLXNB1 plxnb1 (Catalog #AAA242807) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human PLXNB1 / Plexin-B1 reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PLXNB1 / Plexin-B1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA (1:10000), IHC-P (5 ug/ml), WB (1:200). Researchers should empirically determine the suitability of the PLXNB1 plxnb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLXNB1 / Plexin-B1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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