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Immunohistochemistry (IHC)
(Anti-MRGPRX4 / MRGX4 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit anti-Human MRGPRX4 / MRGX4 Polyclonal Antibody | anti-MRGPRX4 antibody
Rabbit Polyclonal to Human MRGPRX4 / MRGX4
Gene Names
MRGPRX4; GPCR; MRGX4; SNSR6
Reactivity
Human
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
MRGPRX4 / MRGX4; Polyclonal Antibody; Rabbit Polyclonal to Human MRGPRX4 / MRGX4; Anti-MRGPRX4 / MRGX4 Antibody (C-Terminus) IHC-plus; MRGPRX4; MRGX4; SNSR6; SNSR5; MAS-related GPR; member X4; Human MRGPRX4; anti-MRGPRX4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Human MRGPRX4 / MRGX4. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MRGPRX3 (67%), MRGPRX1 (67%), ALMS1 (44%).
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
322
Applicable Applications for anti-MRGPRX4 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (3 - 16 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 18 amino acid peptide from C-terminus of human MRGPRX4 / MRGX4. Percent identity with other species by BLAST analysis: Human (100%); Gorilla (89%).
Immunogen Type
Synthetic peptide
Immunogen
MRGPRX4 / MRGX4 antibody was raised against synthetic 18 amino acid peptide from C-terminus of human MRGPRX4 / MRGX4. Percent identity with other species by BLAST analysis: Human (100%); Gorilla (89%).
Antigen Modification
C-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Immunohistochemistry (IHC)
(Anti-MRGPRX4 / MRGX4 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-MRGPRX4 / MRGX4 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-MRGPRX4 / MRGX4 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-MRGPRX4 / MRGX4 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-MRGPRX4 / MRGX4 antibody IHC of human spinal cord, dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-MRGPRX4 / MRGX4 antibody IHC of human spinal cord, dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-MRGPRX4 / MRGX4 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-MRGPRX4 / MRGX4 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-MRGPRX4 antibody
MRGX4 is an Orphan-A GPCR with an unknown ligand highly similar to other MRG receptors. MRGX4 has been suggested to function in sensory neuron regulation and in the modulation of nociception.
Product Categories/Family for anti-MRGPRX4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36,461 Da
NCBI Official Full Name
mas-related G-protein coupled receptor member X4
NCBI Official Synonym Full Names
MAS-related GPR, member X4
NCBI Official Symbol
MRGPRX4
NCBI Official Synonym Symbols
GPCR; MRGX4; SNSR6
NCBI Protein Information
mas-related G-protein coupled receptor member X4; G protein-coupled receptor MRGX4; G protein-coupled receptor SNSR5; G protein-coupled receptor SNSR6; sensory neuron-specific G-protein coupled receptor 5/6
UniProt Protein Name
Mas-related G-protein coupled receptor member X4
Protein Family
UniProt Gene Name
MRGPRX4
UniProt Synonym Gene Names
MRGX4; SNSR5; SNSR6
UniProt Entry Name
MRGX4_HUMAN
Uniprot Description
MRGPRX4: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins. Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11p15.1
Cellular Component: integral to membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway
Research Articles on MRGPRX4
Similar Products
Product Notes
The MRGPRX4 mrgprx4 (Catalog #AAA242712) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human MRGPRX4 / MRGX4 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MRGPRX4 / MRGX4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (3 - 16 ug/ml). Researchers should empirically determine the suitability of the MRGPRX4 mrgprx4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRGPRX4 / MRGX4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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