Rabbit RAB8B Polyclonal Antibody | anti-RAB8B antibody

Anti-RAB8B Antibody (C-Terminus)

Cat. Num. AAA2401780

• Reactivity: Human; Predicted: Mouse, Bovine, Rat
• Applications: Immunohistochemistry, Western Blot
• Purity: Immunoaffinity Purified
• Synonyms: RAB8B; Polyclonal Antibody; Anti-RAB8B Antibody (C-Terminus); Rabbit Polyclonal to Human RAB8B; RAB-8b protein; Ras-related protein Rab-8B; anti-RAB8B antibody

• Host: Rabbit
• Reactivity: Human; Predicted: Mouse, Bovine, Rat
• Clonality: Polyclonal
• Specificity: Recognizes endogenous levels of RAB8B protein.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, pH 7.3, 0.01% sodium azide, 30% glycerol.
• Sequence Length: 207

• Applicable Applications for anti-RAB8B antibody: Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
• Application Notes: IHC-P: 1:100; WB: 1:500-1:1000
• Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-terminal region of human RAB8B.
• Conjugation: Unconjugated
• Epitope: C-Terminus
• Preparation and Storage: Aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (WB)

(Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot analysis of RAB8B expression in COLO205 (A); NS-1 (B); PC12 (C) whole cell lysates.)

Related Product Information for anti-RAB8B antibody

The small GTPases Rab are key regulators of intracellular membranetrafficking, from the formation of transport vesicles to their fusionwith membranes. Rabs cycle between an inactive GDP-bound form and anactive GTP-bound form that is able to recruit to membranes differentsets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarizedvesicular trafficking and neurotransmitter release.

Product Categories/Family for anti-RAB8B antibody

Ras GTPase superfamily IPR001806

NCBI and Uniprot Product Information

• NCBI GI #: 7706563
• NCBI GeneID: 51762
• NCBI Accession #: NP_057614.1
• NCBI GenBank Nucleotide #: NM_016530.2
• UniProt Accession #: Q92930; Q5JPC4; Q9P293
• Molecular Weight: 23,584 Da
• NCBI Official Full Name: ras-related protein Rab-8B
• NCBI Official Synonym Full Names: RAB8B, member RAS oncogene family
• NCBI Official Symbol: RAB8B
• NCBI Protein Information: ras-related protein Rab-8B
• UniProt Protein Name: Ras-related protein Rab-8B
• Protein Family: Ras-related protein
• UniProt Gene Name: RAB8B

NCBI Description

RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al., 1997 [PubMed 9030196]).[supplied by OMIM, Nov 2010]

Uniprot Description

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells ().