Sheep TGN46 Polyclonal Antibody | anti-TGN46 antibody
SHEEP ANTI HUMAN TGN46
Gene Names
TGOLN2; TGN38; TGN46; TGN48; TGN51; TTGN2
Reactivity
React with: PrimateN.B. Antibody reactivity and working conditions may vary between species.
Applications
Immunohistochemistry, Immunofluorescence, Western Blot
Synonyms
TGN46; Polyclonal Antibody; SHEEP ANTI HUMAN TGN46; TGOLN2; anti-TGN46 antibody
Host
Sheep
Reactivity
React with: Primate
N.B. Antibody reactivity and working conditions may vary between species.
N.B. Antibody reactivity and working conditions may vary between species.
Clonality
Polyclonal
Isotype
IgG
Specificity
TGN46
Form/Format
Purified, Liquid
Concentration
IgG concentration 0.25mg/ml (varies by lot)
Sequence Length
480
Applicable Applications for anti-TGN46 antibody
Immunohistology Frozen*, Immunofluorescence (IF), Western Blot (WB)
Application Notes
Immunohistology - Frozen: Minimum Dilution: 0.1ug/ml; Maximum Dilution: 1ug/ml; Application Note: Fixation with 3% paraformaldehyde or methanol/acetone is recommended.
Western Blotting: Minimum Dilution: 0.1ug/ml; Maximum Dilution: 1ug/ml
Western Blotting: Minimum Dilution: 0.1ug/ml; Maximum Dilution: 1ug/ml
Perservative Stabilisers
0.02% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin
25% Glycerol
0.5% Bovine Serum Albumin
25% Glycerol
Immunogen
Recombinant human TGN46
Buffer Solution
Phosphate buffered saline
Antiserum Preparation
Antisera to human TGN46 were raised by repeated immunisation of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography.
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-TGN46 antibody
Sheep anti Human TGN46 antibody recognizes Trans-Golgi network integral membrane protein 2 (TGOLN2), also known as TGN38 homolog, TGN46, TGN48 or Trans-Golgi network protein TGN51. TGN46 is a 437 amino acid glycoprotein localized to the Trans-Golgi network. TGN46 has been reported as being the best available marker for human trans-Golgi network.
TGN46 is a heavily glycosylated protein of around 110-120 kDa. Multiple isoforms of TGN46 are generated by alternative splicing difffering in sequence at the C-terminal protion. Sheep anti Human TGN46 antibody is expeced to recognize all identified isoforms.
TGN46 is a heavily glycosylated protein of around 110-120 kDa. Multiple isoforms of TGN46 are generated by alternative splicing difffering in sequence at the C-terminal protion. Sheep anti Human TGN46 antibody is expeced to recognize all identified isoforms.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
trans-Golgi network integral membrane protein 2 isoform 2
NCBI Official Synonym Full Names
trans-golgi network protein 2
NCBI Official Symbol
TGOLN2
NCBI Official Synonym Symbols
TGN38; TGN46; TGN48; TGN51; TTGN2
NCBI Protein Information
trans-Golgi network integral membrane protein 2; TGN38 homolog; trans-Golgi network protein (46, 48, 51kD isoforms); trans-Golgi network protein TGN51
UniProt Protein Name
Trans-Golgi network integral membrane protein 2
UniProt Gene Name
TGOLN2
UniProt Synonym Gene Names
TGN46; TGN51
UniProt Entry Name
TGON2_HUMAN
NCBI Description
This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Uniprot Description
TGOLN2: May be involved in regulating membrane traffic to and from trans-Golgi network. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 2p11.2
Cellular Component: nucleoplasm; Golgi apparatus; transport vesicle; integral to membrane; plasma membrane; trans-Golgi network
Molecular Function: protein binding
Research Articles on TGN46
Similar Products
Product Notes
The TGN46 tgoln2 (Catalog #AAA223409) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The SHEEP ANTI HUMAN TGN46 reacts with React with: Primate N.B. Antibody reactivity and working conditions may vary between species. and may cross-react with other species as described in the data sheet. AAA Biotech's TGN46 can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen*, Immunofluorescence (IF), Western Blot (WB). Immunohistology - Frozen: Minimum Dilution: 0.1ug/ml; Maximum Dilution: 1ug/ml; Application Note: Fixation with 3% paraformaldehyde or methanol/acetone is recommended. Western Blotting: Minimum Dilution: 0.1ug/ml; Maximum Dilution: 1ug/ml. Researchers should empirically determine the suitability of the TGN46 tgoln2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TGN46, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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