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Sheep anti-Mouse TGN38 Polyclonal Antibody | anti-TGN38 antibody

SHEEP ANTI RAT TGN38

Gene Names
Tgoln2; Tgn38; Ttgn1; Tgoln1
Reactivity
Mouse
Applications
Immunohistochemistry, Immunofluorescence, Western Blot
Synonyms
TGN38; Polyclonal Antibody; SHEEP ANTI RAT TGN38; anti-TGN38 antibody
Ordering
For Research Use Only!
Host
Sheep
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Form/Format
Serum
serum diluted - liquid
Sequence Length
357
Applicable Applications for anti-TGN38 antibody
Immunohistology Frozen, Immunoelectron Microscopy (EM), Immunofluorescence (IF), Western Blot (WB)
Application Notes
Immunohistology: Fixation with methanol or methanol/acetone recommended.
Immunohistology - Frozen: Minimum Dilution: 1/100; Maximum Dilution: 1/200
Western Blotting: Maximum Dilution: 1/1000
Perservative Stabilisers
0.09% Sodium Azide
Buffer Solution
Phosphate buffered saline
Antiserum Preparation
Antisera to TGN38 were raised by repeated immunisations of sheep with highly purified antigen.
Target Species
Rat
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-TGN38 antibody
Sheep anti Rat TGN38 antibody recognizes rat TGN38, a 357 amino acid single pass trans membrane glycoprotein found primarily in the Trans-golgi network, and acts as an excellent marker for this cellular organelle (Humphrey et al. 1993). TGN38 is likely to have a role in intracellular transport (McNamara et al. 2004) and plays a role in morphological maintenance (Girotti and Banting 1996). It is the homologue of human TGN46 and macaque TGN47 (Ponnambalam et al. 1996).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,305 Da
NCBI Official Full Name
trans-Golgi network integral membrane protein TGN38
NCBI Official Synonym Full Names
trans-golgi network protein 2
NCBI Official Symbol
Tgoln2
NCBI Official Synonym Symbols
Tgn38; Ttgn1; Tgoln1
NCBI Protein Information
trans-Golgi network integral membrane protein TGN38; trans-golgi network protein 1
UniProt Protein Name
Trans-Golgi network integral membrane protein TGN38
UniProt Gene Name
Ttgn1
UniProt Entry Name
TGON3_RAT

NCBI Description

resident integral membrane proteins of the trans-Golgi network (TGN), cycles constitutively between the TGN and the plasma membrane [RGD, Feb 2006]

Uniprot Description

TGOLN2: May be involved in regulating membrane traffic to and from trans-Golgi network. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: nucleoplasm; Golgi apparatus; trans-Golgi network transport vesicle; integral to membrane; trans-Golgi network; nucleus; endosome

Molecular Function: protein binding

Biological Process: Golgi to endosome transport

Research Articles on TGN38

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Product Notes

The TGN38 ttgn1 (Catalog #AAA223177) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The SHEEP ANTI RAT TGN38 reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TGN38 can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen, Immunoelectron Microscopy (EM), Immunofluorescence (IF), Western Blot (WB). Immunohistology: Fixation with methanol or methanol/acetone recommended. Immunohistology - Frozen: Minimum Dilution: 1/100; Maximum Dilution: 1/200 Western Blotting: Maximum Dilution: 1/1000. Researchers should empirically determine the suitability of the TGN38 ttgn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TGN38, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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