Rabbit ARG VASOPRESSIN RECEPTOR Polyclonal Antibody | anti-Avpr2 antibody
RABBIT ANTI RAT ARG VASOPRESSIN RECEPTOR
Purified IgG - liquid
0.1% Bovine Serum Albumin
Preparation
Buffer Solution
Shelf Life: 18 months from date of despatch.
NCBI and Uniprot Product Information
NCBI Description
G-protein coupled receptor for arginine vasopressin; responsible for mediation of antidiuretic effect and changes in blood pressure [RGD, Feb 2006]
Uniprot Description
AVPR2: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption. Defects in AVPR2 are the cause of nephrogenic syndrome of inappropriate antidiuresis (NSIAD). This disorder is characterized by an inability to excrete a free water load, with inappropriately concentrated urine and resultant hyponatremia, hypoosmolarity, and natriuresis. Defects in AVPR2 are the cause of diabetes insipidus nephrogenic X-linked (XNDI); also known as diabetes insipidus nephrogenic type 1. XNDI is caused by the inability of the renal collecting ducts to absorb water in response to arginine vasopressin. It is characterized by excessive water drinking (polydypsia), excessive urine excretion (polyuria), persistent hypotonic urine, and hypokalemia. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Transporter; Transporter, aquaporin family
Cellular Component: integral to plasma membrane; integral to membrane; intracellular
Molecular Function: peptide hormone binding; vasopressin receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; I-kappaB kinase/NF-kappaB cascade; telencephalon development; regulation of systemic arterial blood pressure by vasopressin; response to cytokine stimulus; positive regulation of cell proliferation; positive regulation of vasoconstriction; interferon-gamma production; positive regulation of systemic arterial blood pressure; positive regulation of blood pressure; cellular response to hormone stimulus
Research Articles on Avpr2
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Product Notes
The Avpr2 avpr2 (Catalog #AAA221213) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI RAT ARG VASOPRESSIN RECEPTOR reacts with Bovine (Expected from Sequence), Human (Expected from Sequence), Mouse (Expected from Sequence), Pig (Expected from Sequence) and may cross-react with other species as described in the data sheet. AAA Biotech's ARG VASOPRESSIN RECEPTOR can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen, ELISA (EIA), Western Blot (WB). Western Blot: A glycosylated band at approximately 62 kD is observed using membranes from rat inner medulla. N-Glycanase reduces the size of this band to 36 kD (deglycosylated form). Researchers should empirically determine the suitability of the Avpr2 avpr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARG VASOPRESSIN RECEPTOR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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