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Rabbit IP-10 Polyclonal Antibody | anti-IP-10 antibody

RABBIT ANTI MOUSE IP-10:Biotin

Gene Names
Cxcl10; C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10
Applications
ELISA, Western Blot
Synonyms
IP-10; Polyclonal Antibody; RABBIT ANTI MOUSE IP-10:Biotin; anti-IP-10 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Form/Format
Biotin
Purified IgG conjugated to Biotin - lyophilised
Concentration
IgG concentration 0.1 mg/ml after reconstitution (varies by lot)
Sequence Length
98
Applicable Applications for anti-IP-10 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: Biotinylated rabbit anti mouse IP-10 may be used in a direct ELISA or as a detection reagent in a sandwich ELISA with our purified anti mouse IP-10 antibody as a capture reagent and recombinant mouse IP-10 as the standard.
ELISA: Minimum Dilution: 0.5; Maximum Dilution: 2.0ug/ml
Western Blotting: Minimum Dilution: 0.1ug/ml; Maximum Dilution: 0.2ug/ml
Reconstitution
Reconstitute with 0.5 ml distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. MyBioSource recommends that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.
Immunogen
Recombinant mouse IP-10
Buffer Solution
Antiserum Preparation
Antisera to mouse IP-10 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Target Species
Mouse
Preparation and Storage
Prior to reconstitution store at 4 degree C. Following reconstitution store at -20 degree C. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.
Related Product Information for anti-IP-10 antibody
Rabbit anti Mouse IP-10 antibody recognizes interferon gamma inducible protein (IP-10), also known as CXCL10. IP-10 is expressed in a variety of tissues including liver, gut, spleen, kidney and thymus, in response to interferon gamma. IP-10 acts as a chemoattractant for monocytes, NK cells and certain T-cells.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,789 Da
NCBI Official Full Name
C-X-C motif chemokine 10
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 10
NCBI Official Symbol
Cxcl10
NCBI Official Synonym Symbols
C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10
NCBI Protein Information
C-X-C motif chemokine 10; 10 kDa interferon gamma-induced protein; gamma-IP10; interferon activated gene 10; interferon-gamma induced protein CRG-2; interferon-gamma-induced protein CRG-2; small inducible cytokine B subfamily (Cys-X-Cys), member 10; small-inducible cytokine B10
UniProt Protein Name
C-X-C motif chemokine 10
UniProt Gene Name
Cxcl10
UniProt Synonym Gene Names
Crg2; Ifi10; Inp10; Scyb10; Gamma-IP10; IP-10
UniProt Entry Name
CXL10_MOUSE

Uniprot Description

CXCL10: Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Chemokine; Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Cellular Component: extracellular space; cell; extracellular region; external side of plasma membrane

Molecular Function: heparin binding; CXCR3 chemokine receptor binding; chemokine activity; cytokine activity

Biological Process: positive regulation of leukocyte chemotaxis; response to lipopolysaccharide; positive regulation of cAMP metabolic process; chemotaxis; regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; negative regulation of angiogenesis; positive regulation of cell proliferation; immune response; positive regulation of release of sequestered calcium ion into cytosol; negative regulation of myoblast differentiation; inflammatory response; defense response to virus; positive regulation of cell migration

Research Articles on IP-10

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Product Notes

The IP-10 cxcl10 (Catalog #AAA220127) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IP-10 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: Biotinylated rabbit anti mouse IP-10 may be used in a direct ELISA or as a detection reagent in a sandwich ELISA with our purified anti mouse IP-10 antibody as a capture reagent and recombinant mouse IP-10 as the standard. ELISA: Minimum Dilution: 0.5; Maximum Dilution: 2.0ug/ml Western Blotting: Minimum Dilution: 0.1ug/ml; Maximum Dilution: 0.2ug/ml. Researchers should empirically determine the suitability of the IP-10 cxcl10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IP-10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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