Rabbit IL-1 BETA Polyclonal Antibody | anti-IL1B antibody
RABBIT ANTI CHICKEN INTERLEUKIN-1 BETA:Preservative Free
Gene Names
IL1B; IL1beta; IL-1BETA
Applications
ELISA, Functional Assay, Western Blot
Synonyms
IL-1 BETA; Polyclonal Antibody; RABBIT ANTI CHICKEN INTERLEUKIN-1 BETA:Preservative Free; anti-IL1B antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
This item recognizes chicken Interleukin 1 beta (chIL-1beta), which shares
homology with mammalian IL-1beta.
IL-1 is a major regulator in both innate and adaptive immune responses, plays an important role in the regulation of acute inflammation and has also been implicated in many other processes, including both fever and fibrinogen induction. The previous names by which IL-1 has been known includes lymphocyte activating factor, endogenous pyrogen, catabolin, hemopoietin-1, melanoma growth inhibition factor, and osteoclast activating factor, reflecting its widespread cell expression.
Studies using chicken models have indicated physiological similarities between chIL-1beta and mammalian IL-1beta in relation to its neural distribution and several factors have been shown to induce chIL-1beta secretion, including protein kinase C (PKC), Calmodulin-dependent protein kinase, lipopolysaccharide, phorbol esters, calcium and silica.
This item neutralizes chicken IL-1 beta (1-2).
homology with mammalian IL-1beta.
IL-1 is a major regulator in both innate and adaptive immune responses, plays an important role in the regulation of acute inflammation and has also been implicated in many other processes, including both fever and fibrinogen induction. The previous names by which IL-1 has been known includes lymphocyte activating factor, endogenous pyrogen, catabolin, hemopoietin-1, melanoma growth inhibition factor, and osteoclast activating factor, reflecting its widespread cell expression.
Studies using chicken models have indicated physiological similarities between chIL-1beta and mammalian IL-1beta in relation to its neural distribution and several factors have been shown to induce chIL-1beta secretion, including protein kinase C (PKC), Calmodulin-dependent protein kinase, lipopolysaccharide, phorbol esters, calcium and silica.
This item neutralizes chicken IL-1 beta (1-2).
Form/Format
Preservative Free
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 0.5 mg/ml (varies by lot)
Sequence Length
267
Applicable Applications for anti-IL1B antibody
ELISA (EIA), Functional Assays (FN), Western Blot (WB)
Application Notes
Western Blot: This item detects a band of approximately 29kDa in HD-11 cell lysates transfected with chIL-1.
Immunogen
Recombinant chicken IL-1beta
Buffer Solution
Buffer Solution
Antiserum Preparation
Antisera to chicken Interleukin-1beta were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography on protein G.
Target Species
Chicken
Preparation and Storage
Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-IL1B antibody
MBS220072 recognizes chicken Interleukin 1 beta (chIL-1beta), which shares homology with mammalian IL-1beta. IL-1 is a major regulator in both innate and adaptive immune responses, plays an important role in the regulation of acute inflammation and has also been implicated in many other processes, including both fever and fibrinogen induction. The previous names by which IL-1 has been known includes lymphocyte activating factor, endogenous pyrogen, catabolin, hemopoietin-1, melanoma growth inhibition factor, and osteoclast activating factor, reflecting its widespread cell expression. Studies using chicken models have indicated physiological similarities between chIL-1beta and mammalian IL-1beta in relation to its neural distribution and several factors have been shown to induce chIL-1beta secretion, including protein kinase C (PKC), Calmodulin-dependent protein kinase, lipopolysaccharide, phorbol esters, calcium and silica. MBS220072 neutralizes chicken IL-1 beta (1-2).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
interleukin-1 beta
NCBI Official Synonym Full Names
interleukin 1, beta
NCBI Official Symbol
IL1B
NCBI Official Synonym Symbols
IL1beta; IL-1BETA
NCBI Protein Information
interleukin-1 beta; IL-1 beta
Protein Family
Research Articles on IL1B
Similar Products
Product Notes
The IL1B (Catalog #AAA220072) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IL-1 BETA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Functional Assays (FN), Western Blot (WB). Western Blot: This item detects a band of approximately 29kDa in HD-11 cell lysates transfected with chIL-1. Researchers should empirically determine the suitability of the IL1B for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-1 BETA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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