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Rat EPSTEIN-BARR VIRUS LMP2A Monoclonal Antibody

RAT ANTI EPSTEIN-BARR VIRUS LMP2A

Applications
Immunohistochemistry, Western Blot
Synonyms
EPSTEIN-BARR VIRUS LMP2A; Monoclonal Antibody; RAT ANTI EPSTEIN-BARR VIRUS LMP2A; EBV; anti-EPSTEIN-BARR VIRUS LMP2A antibody
Ordering
For Research Use Only!
Host
Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
15F9
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (varies by lot)
Applicable Applications for anti-EPSTEIN-BARR VIRUS LMP2A antibody
Immunohistology Paraffin*, Western Blot (WB)
Application Notes
Western Blotting: < 1/100- 1/1000
Perservative Stabilisers
0.09% Sodium Azide
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Carrier Free
Yes
Fusion Partners
Spllen cells from immunized Lou/C rats were fused with cells of the P3X63.Ag8.653 myeloma cell line.
Immunogen
Bacterial TrpE-LMP2A fusion protein
Fusion Partners
Target Species
Viral
Preparation and Storage
Store at 4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-EPSTEIN-BARR VIRUS LMP2A antibody
Rat anti Epstein-Barr Virus LMP2A antibody, clone 15F9 recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpesvirus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. MBS212822 specifically recognizes LMP2A and does not cross react with LMP2B.

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Product Notes

The EPSTEIN-BARR VIRUS LMP2A (Catalog #AAA212822) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's EPSTEIN-BARR VIRUS LMP2A can be used in a range of immunoassay formats including, but not limited to, Immunohistology Paraffin*, Western Blot (WB). Western Blotting: < 1/100- 1/1000. Researchers should empirically determine the suitability of the EPSTEIN-BARR VIRUS LMP2A for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EPSTEIN-BARR VIRUS LMP2A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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