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Mouse anti-Human Chemokine (C-X-C Motif) Ligand 27 (CCL27) Monoclonal Antibody | anti-CCL27 antibody

APC-Linked Monoclonal Antibody to Chemokine (C-X-C Motif) Ligand 27 (CCL27)

Gene Names
CCL27; ALP; ILC; CTAK; CTACK; PESKY; ESKINE; SCYA27
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
Purity
Protein A + Protein G Affinity Chromatography
Synonyms
Chemokine (C-X-C Motif) Ligand 27 (CCL27); Monoclonal Antibody; APC-Linked Monoclonal Antibody to Chemokine (C-X-C Motif) Ligand 27 (CCL27); CTACK; ILC; SCYA27; ALP; Skinkine; ESkine; PESKY; CTAK; Cutaneous T-Cell Attracting Chemokine; Small Inducible Cytokine Subfamily A Member 27; IL-11 R-alpha-locus chemokine; anti-CCL27 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a Kappa
Clone Number
C7
Specificity
The antibody is a mouse monoclonal antibody raised against CCL27. It has been selected for its ability to recognize CCL27 in immunohistochemical staining and western blotting.
Purity/Purification
Protein A + Protein G Affinity Chromatography
Form/Format
Liquid; 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Concentration
>=100ug/ml (varies by lot)
Sequence
Phe25~Gly112
Applicable Applications for anti-CCL27 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Immunogen Sequence
Phe25~Gly112
Cross Reactivity
Human
Conjugation
APC
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Product Categories/Family for anti-CCL27 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12,618 Da
NCBI Official Full Name
C-C motif chemokine 27
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 27
NCBI Official Symbol
CCL27
NCBI Official Synonym Symbols
ALP; ILC; CTAK; CTACK; PESKY; ESKINE; SCYA27
NCBI Protein Information
C-C motif chemokine 27; skinkine; CC chemokine ILC; IL-11 Ralpha-locus chemokine; small-inducible cytokine A27; IL-11 R-alpha-locus chemokine; cutaneous T-cell attracting chemokine; cutaneous T-cell-attracting chemokine; small inducible cytokine subfamily
UniProt Protein Name
C-C motif chemokine 27
Protein Family
UniProt Gene Name
CCL27
UniProt Synonym Gene Names
ILC; SCYA27; CTACK
UniProt Entry Name
CCL27_HUMAN

NCBI Description

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Jul 2008]

Uniprot Description

CCL27: Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. May play a role in cell migration during embryogenesis. Nuclear forms may facilitate cellular migration by inducing cytoskeletal relaxation. Binds to CCR10. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Chemokine; Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 9p13

Cellular Component: extracellular space; extracellular region

Molecular Function: chemokine activity

Biological Process: cell-cell signaling; immune response; chemotaxis

Research Articles on CCL27

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Product Notes

The CCL27 ccl27 (Catalog #AAA2119969) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The APC-Linked Monoclonal Antibody to Chemokine (C-X-C Motif) Ligand 27 (CCL27) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Chemokine (C-X-C Motif) Ligand 27 (CCL27) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the CCL27 ccl27 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Phe25~Gly1 12. It is sometimes possible for the material contained within the vial of "Chemokine (C-X-C Motif) Ligand 27 (CCL27), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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