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Immunohistochemistry (IHC) (DAB staining on IHC-P;Samples: Human Cerebrum Tissue; Primary Ab: 10ug/ml Mouse Anti-Human CSNK1d AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody)

Mouse anti-Human Casein Kinase 1 Delta (CSNK1d) Monoclonal Antibody | anti-CSNK1d antibody

Monoclonal Antibody to Casein Kinase 1 Delta (CSNK1d)

Gene Names
CSNK1D; ASPS; CKId; HCKID; FASPS2; CKIdelta; CKI-delta
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
Purity
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Synonyms
Casein Kinase 1 Delta (CSNK1d); Monoclonal Antibody; Monoclonal Antibody to Casein Kinase 1 Delta (CSNK1d); Enzyme & Kinase; anti-CSNK1d antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Specificity
The antibody is a mouse monoclonal antibody raised against CSNK1d. It has been selected for its ability to recognize CSNK1d in immunohistochemical staining and western blotting.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Concentration
1mg/mL (varies by lot)
Sequence
Met1~Arg415
Sequence Length
415
Applicable Applications for anti-CSNK1d antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes
WB: 0.2-2ug/mL; 1:500-5000
IHC: 5-20ug/mL; 1:50-200
ICC: 5-20ug/mL; 1:50-200
Conjugation
None
Cross Reactivity
Human
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Immunohistochemistry (IHC)

(DAB staining on IHC-P;Samples: Human Cerebrum Tissue; Primary Ab: 10ug/ml Mouse Anti-Human CSNK1d AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody)

Immunohistochemistry (IHC) (DAB staining on IHC-P;Samples: Human Cerebrum Tissue; Primary Ab: 10ug/ml Mouse Anti-Human CSNK1d AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
casein kinase I isoform delta isoform 1
NCBI Official Synonym Full Names
casein kinase 1 delta
NCBI Official Symbol
CSNK1D
NCBI Official Synonym Symbols
ASPS; CKId; HCKID; FASPS2; CKIdelta; CKI-delta
NCBI Protein Information
casein kinase I isoform delta; casein kinase I
UniProt Protein Name
Casein kinase I isoform delta
Protein Family
UniProt Gene Name
CSNK1D
UniProt Synonym Gene Names
HCKID; CKI-delta; CKId
UniProt Entry Name
KC1D_HUMAN

NCBI Description

This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]

Uniprot Description

CK1D: an ubiquitous protein kinase of the CK1 family. Enriched at the centrosomes in interphase and at the spindle during mitosis. May play a role in cell cycle progression. Two splice variant isoforms have been described.

Protein type: EC 2.7.11.26; Protein kinase, CK1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.1; CK1 group; CK1 family

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: Golgi apparatus; centrosome; spindle microtubule; perinuclear region of cytoplasm; plasma membrane; spindle; nucleus; cytosol

Molecular Function: protein serine/threonine kinase activity; protein binding; tau-protein kinase activity; phosphoprotein binding; glycoprotein binding; peptide binding; ATP binding; protein kinase activity

Biological Process: Wnt receptor signaling pathway; organelle organization and biogenesis; endocytosis; spindle assembly; signal transduction; regulation of circadian rhythm; DNA repair; protein amino acid phosphorylation; regulation of cell shape; peptidyl-serine phosphorylation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of protein amino acid phosphorylation; mitotic cell cycle; circadian regulation of gene expression; G2/M transition of mitotic cell cycle

Disease: Advanced Sleep Phase Syndrome, Familial, 2

Research Articles on CSNK1d

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Product Notes

The CSNK1d csnk1d (Catalog #AAA2111298) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to Casein Kinase 1 Delta (CSNK1d) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Casein Kinase 1 Delta (CSNK1d) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). WB: 0.2-2ug/mL; 1:500-5000 IHC: 5-20ug/mL; 1:50-200 ICC: 5-20ug/mL; 1:50-200. Researchers should empirically determine the suitability of the CSNK1d csnk1d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Met1~Arg41 5. It is sometimes possible for the material contained within the vial of "Casein Kinase 1 Delta (CSNK1d), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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