Rabbit anti-Mouse Permeability Glycoprotein (Pgp) Polyclonal Antibody | anti-Pgp antibody
APC/Cy7 Linked Polyclonal Antibody to Permeability Glycoprotein (Pgp)
Gene Names
Abcb1b; mdr; Mdr1; Pgy1; Abcb1; Mdr1b; Pgy-1
Reactivity
Mouse
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
Purity
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Synonyms
Permeability Glycoprotein (Pgp); Polyclonal Antibody; APC/Cy7 Linked Polyclonal Antibody to Permeability Glycoprotein (Pgp); CD243; ABCB1; ABC20; CLCS; GP170; MDR1; PGY1; P-Glycoprotein; Multidrug resistance protein 1; ATP-Binding Cassette; Sub-Family B (MDR/TAP); Member 1; Colchicin Sensitivity; anti-Pgp antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Specificity
The antibody is a Rabbit polyclonal antibody raised against Pgp. It has been selected for its ability to recognize Pgp in immunohistochemical staining and western blotting.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Form/Format
Liquid
Concentration
>=100ug/ml (varies by lot)
Sequence Length
1276
Applicable Applications for anti-Pgp antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Conjugation
APC-Cy7
Cross Reactivity
Mouse
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
multidrug resistance protein 1B
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family B (MDR/TAP), member 1B
NCBI Official Symbol
Abcb1b
NCBI Official Synonym Symbols
mdr; Mdr1; Pgy1; Abcb1; Mdr1b; Pgy-1
NCBI Protein Information
multidrug resistance protein 1B
UniProt Protein Name
Multidrug resistance protein 1B
Protein Family
UniProt Gene Name
Abcb1b
UniProt Synonym Gene Names
Abcb1; Mdr1; Mdr1b; Pgy1; Pgy1-1
NCBI Description
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene encodes a membrane glycoprotein which confers a multidrug-resistance phenotype. The protein encoded by the human gene is an ATP-dependent drug efflux pump for xenobiotic compounds which is responsible for decreased drug accumulation in multidrug-resistant cells and mediates the development of resistance to anticancer drugs. [provided by RefSeq, Jul 2008]
Uniprot Description
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Research Articles on Pgp
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Product Notes
The Pgp abcb1b (Catalog #AAA2108880) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APC/Cy7 Linked Polyclonal Antibody to Permeability Glycoprotein (Pgp) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Permeability Glycoprotein (Pgp) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the Pgp abcb1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Permeability Glycoprotein (Pgp), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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