T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Recombinant Protein | CD3g recombinant protein

Recombinant T-Cell Surface Glycoprotein CD3 Gamma (CD3g)

Cat. Num. AAA2105441

• Gene Names: CD3G; T3G; IMD17; CD3-GAMMA
• Applications: SDS-Page, Western Blot
• Purity: > 80%
• Synonyms: T-Cell Surface Glycoprotein CD3 Gamma (CD3g); Recombinant T-Cell Surface Glycoprotein CD3 Gamma (CD3g); T3G; CD3-G; CD3g Molecule; Gamma(CD3-TCR Complex); CD3-GAMMA; CD3g recombinant protein

• Host: Host: E Coli; Source: Prokaryotic Expression
• Purity/Purification: > 80%
• Form/Format: Freeze-Dried Powder; PBS, pH7.4, Containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Sequence Positions: Gln23~Asn182
• Sequence Length: 182

• Applicable Applications for CD3g recombinant protein: Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
• Species: Human
• Tag: N-terminal His-Tag
• Isoelectric Point: 8.6
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Subcellular Location: Membrane
• Reconstitution: Reconstitute in PBS or others.
• Preparation and Storage: Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Product Categories/Family for CD3g recombinant protein

Immune molecule

NCBI and Uniprot Product Information

• NCBI GI #: 4557429
• NCBI GeneID: 917
• NCBI Accession #: NP_000064.1
• NCBI GenBank Nucleotide #: NM_000073.2
• UniProt Accession #: P09693
• Molecular Weight: Predicted MW: 21.9kDa; Accurate MW: 20kDa
• NCBI Official Full Name: T-cell surface glycoprotein CD3 gamma chain
• NCBI Official Synonym Full Names: CD3g molecule
• NCBI Official Symbol: CD3G
• NCBI Official Synonym Symbols: T3G; IMD17; CD3-GAMMA
• NCBI Protein Information: T-cell surface glycoprotein CD3 gamma chain
• UniProt Protein Name: T-cell surface glycoprotein CD3 gamma chain
• Protein Family: T-cell surface glycoprotein
• UniProt Gene Name: CD3G
• UniProt Synonym Gene Names: T3G
• UniProt Entry Name: CD3G_HUMAN

NCBI Description

The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq, Jul 2008]

Uniprot Description

CD3G: The CD3 complex mediates signal transduction.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 11q23

Cellular Component: T cell receptor complex; integral to plasma membrane; plasma membrane; alpha-beta T cell receptor complex

Molecular Function: receptor signaling complex scaffold activity; transmembrane receptor activity; protein heterodimerization activity; T cell receptor binding

Biological Process: protein transport; regulation of immune response; cell surface receptor linked signal transduction; T cell activation; T cell costimulation; establishment and/or maintenance of cell polarity; innate immune response; protein complex assembly; T cell receptor signaling pathway

Disease: Immunodeficiency 17