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Mouse Complement Component 8b (C8b) Antibody Pair Kit | C8b antibody pair kit

Mouse Complement Component 8b (C8b) Antibody Pair Kit (with Standard)

Gene Names
C8B; C82
Reactivity
Mouse
Applications
ELISA, ELISA
Synonyms
Complement Component 8b (C8b); Mouse Complement Component 8b (C8b) Antibody Pair Kit (with Standard); Complement component 8 subunit beta; C8b antibody pair kit
Ordering
For Research Use Only!
Reactivity
Mouse
Applicable Applications for C8b antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
Samples
Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates and Other Biological Fluids
Detection Range
31.2-2000ng/mL
Standard
Recombinant C8b (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
Product Categories/Family for C8b antibody pair kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
732
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
67,047 Da
NCBI Official Full Name
complement component C8 beta chain isoform 3
NCBI Official Synonym Full Names
complement C8 beta chain
NCBI Official Symbol
C8B
NCBI Official Synonym Symbols
C82
NCBI Protein Information
complement component C8 beta chain
UniProt Protein Name
Complement component C8 beta chain
Protein Family
UniProt Gene Name
C8B

NCBI Description

This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

Uniprot Description

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.

Research Articles on C8b

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Product Notes

The Mouse C8b c8b (Catalog #AAA2100182) is an Antibody Pair Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2100182 Antibody Pair Kit recognizes Mouse C8b. AAA Biotech's Complement Component 8b (C8b) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex. Researchers should empirically determine the suitability of the C8b c8b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Complement Component 8b (C8b), Antibody Pair Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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