Glucose Transporter 3 (GLUT3) Recombinant Protein | GLUT3 recombinant protein

Recombinant Glucose Transporter 3 (GLUT3)

Cat. Num. AAA2086786

• Gene Names: SLC2A3; GLUT3
• Applications: SDS-Page, Western Blot
• Purity: > 90%
• Synonyms: Glucose Transporter 3 (GLUT3); Recombinant Glucose Transporter 3 (GLUT3); SLC2A3; Solute Carrier Family 2(Facilitated Glucose Transporter)Member 3; Glucose transporter type 3; brain; GLUT3 recombinant protein

• Host: E Coli
• Purity/Purification: > 90%
• Form/Format: Freeze-dried powder
• Sequence Length: 496

• Applicable Applications for GLUT3 recombinant protein: Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
• Fragment: Pro206~Pro269
• Tag: N-terminal His Tag
• Buffer Formulation: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Source Note: Prokaryotic expression
• Organism Species: Human
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Isoelectric Point: 5.4
• Subcellular Location: Membrane
• Usage: Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Sequence Information

SDS-Page

Testing Data

Product Categories/Family for GLUT3 recombinant protein

Recombinant Protein

NCBI and Uniprot Product Information

• NCBI GI #: 8927560
• NCBI GeneID: 6515
• Molecular Weight: 8.9kDa
• NCBI Official Full Name: glucose transporter 3
• NCBI Official Synonym Full Names: solute carrier family 2 member 3
• NCBI Official Symbol: SLC2A3
• NCBI Official Synonym Symbols: GLUT3
• NCBI Protein Information: solute carrier family 2, facilitated glucose transporter member 3
• UniProt Protein Name: Solute carrier family 2, facilitated glucose transporter member 3
• Protein Family: Glucose transporter
• UniProt Gene Name: SLC2A3
• UniProt Synonym Gene Names: GLUT3; GLUT-3

Uniprot Description

GLUT3: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. It???s surface expression is induced by insulin. It is restricted in humans to brain, testis (in the spermatozoa), and skeletal muscle, mostly in triads of slow-twitch fibres. Detected only in the brain of mouse and rat. IHC demonstrates its present in neurons, mainly at the plasma membrane, and to a lesser extent on intracellular vesicles distinct from synaptic vesicles. Present in the a-granules of human platelets, where it is translocated to the cell surface in response to thrombin stimulation. Its surface expression is increased by insulin or insulin growth-factor in cultured L6 muscle cells.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 12p13.31

Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: D-glucose transmembrane transporter activity; dehydroascorbic acid transporter activity; glucose binding; glucose transmembrane transporter activity

Biological Process: glucose transport; L-ascorbic acid metabolic process