Cytoskeleton Associated Protein 2 Recombinant Protein | CKAP2 recombinant protein

Recombinant Cytoskeleton Associated Protein 2 (CKAP2)

Cat. Num. AAA2034320

• Gene Names: CKAP2; LB1; TMAP; se20-10
• Reactivity: Mouse
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: >90%
• Synonyms: Cytoskeleton Associated Protein 2; Recombinant Cytoskeleton Associated Protein 2 (CKAP2); LB1; TMAP; se20-10; CTCL tumor antigen se20-10; Tumor- and microtubule-associated protein; CKAP2 recombinant protein

• Host: E Coli
• Reactivity: Mouse
• Purity/Purification: >90%
• Sequence Length: 682

• Applicable Applications for CKAP2 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Fragment: Met1~Val250
• Tag: Prokaryotic expression
• Preparation and Storage: Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 187950333
• NCBI GeneID: 26586
• Molecular Weight: 61.7kDa
• NCBI Official Full Name: Cytoskeleton associated protein 2
• NCBI Official Synonym Full Names: cytoskeleton associated protein 2
• NCBI Official Symbol: CKAP2
• NCBI Official Synonym Symbols: LB1; TMAP; se20-10
• NCBI Protein Information: cytoskeleton-associated protein 2
• UniProt Protein Name: Cytoskeleton-associated protein 2
• Protein Family: Cytoskeleton-associated protein
• UniProt Gene Name: CKAP2
• UniProt Entry Name: CKAP2_HUMAN

NCBI Description

This gene encodes a cytoskeleton-associated protein that stabalizes microtubules and plays a role in the regulation of cell division. The encoded protein is itself regulated through phosphorylation at multiple serine and threonine residues. There is a pseudogene of this gene on chromosome 14. Alternative splicing results in multiple transcript variations. [provided by RefSeq, Nov 2013]

Uniprot Description

CKAP2: Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner. Belongs to the CKAP2 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 13q14

Cellular Component: centrosome; cytoplasm; cytoplasmic microtubule; microtubule cytoskeleton; spindle pole

Biological Process: apoptosis; cytokinesis after mitosis; negative regulation of microtubule depolymerization; positive regulation of transcription from RNA polymerase II promoter