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Gene Sequencing (extract)

MOCO Sulphurase C-Terminal Domain Containing Protein 1 Recombinant Protein | MOSC1 recombinant protein

Recombinant MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1)

Gene Names
MARC1; MOSC1
Reactivity
Homo sapiens (Human)
Applications
SDS-Page, Western Blot
Purity
> 97%
Synonyms
MOCO Sulphurase C-Terminal Domain Containing Protein 1; Recombinant MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1); MOSC1 recombinant protein
Ordering
For Research Use Only!
Host
E.coli
Reactivity
Homo sapiens (Human)
Purity/Purification
> 97%
Form/Format
20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
Concentration
Original Concentration: 200ug/mL (varies by lot)
Sequence
RRAWPTRRRR LLQQVGTVAQ LWIYPVKSCK GVPVSEAECT AMGLRSGNLR DRFWLVINQE GNMVTARQEP RLVLISLTCD GDTLTLSAAY TKDLLLPIKT PTTNAVHKCRV HGLEIEGRD CGEATAQWIT SFLKSQPYRL VHFEPHMRPR RPHQIADLFR PKDQIAYSDT SPFLILSEAS LADLNSRLEK KVKATNFRPN IVISGCDVYA EDSWDELLIG DVELKRVMAC SRCILTTVDP DTGVMSRKEP LETLKSYRQC DPSERKLYGK SPLFGQYFVL ENPGTIKVGD PVYLL
Applicable Applications for MOSC1 recombinant protein
Positive Control; Immunogen; SDS-PAGE; Western Blot (WB).
Application Notes
(May be suitable for use in other assays to be determined by the end user.)
Source
Prokaryotic expression
Residues
Arg41~Leu335
Tags
N-terminal His Tag
Subcellular Location
Membrane, Mitochondrion
Traits
Freeze-dried powder
Predicted isoelectric point
8.9
Usage
Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 2-8 degree C for one month.
Aliquot and store at -80 degree C for 12 months.

Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Gene Sequencing (extract)

Gene Sequencing (extract)

SDS-Page

SDS-Page

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
Predicted Molecular Mass: 37.2kDa
Accurate Molecular Mass: 37kDa as determined by SDS-PAGE reducing conditions.
NCBI Official Full Name
MOCO sulphurase C-terminal domain containing 1
NCBI Official Synonym Full Names
mitochondrial amidoxime reducing component 1
NCBI Official Symbol
MARC1
NCBI Official Synonym Symbols
MOSC1
NCBI Protein Information
mitochondrial amidoxime-reducing component 1
UniProt Protein Name
Mitochondrial amidoxime-reducing component 1
UniProt Gene Name
MARC1
UniProt Synonym Gene Names
MOSC1; mARC1; MOSC domain-containing protein 1; Moco sulfurase C-terminal domain-containing protein 1
UniProt Entry Name
MARC1_HUMAN

Uniprot Description

MOSC1: As a component of an N-hydroxylated prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Oxidoreductase; EC 1.-.-.-

Chromosomal Location of Human Ortholog: 1q41

Cellular Component: mitochondrial outer membrane; mitochondrion; mitochondrial inner membrane; integral to membrane

Molecular Function: molybdopterin cofactor binding; nitrate reductase activity; molybdenum ion binding; pyridoxal phosphate binding

Biological Process: detoxification of nitrogen compound; nitrate metabolic process

Research Articles on MOSC1

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Product Notes

The MOSC1 marc1 (Catalog #AAA2031785) is a Recombinant Protein produced from E.coli and is intended for research purposes only. The product is available for immediate purchase. The Recombinant MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1) reacts with Homo sapiens (Human) and may cross-react with other species as described in the data sheet. AAA Biotech's MOCO Sulphurase C-Terminal Domain Containing Protein 1 can be used in a range of immunoassay formats including, but not limited to, Positive Control; Immunogen; SDS-PAGE; Western Blot (WB). (May be suitable for use in other assays to be determined by the end user.). Researchers should empirically determine the suitability of the MOSC1 marc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: RRAWPTRRRR LLQQVGTVAQ LWIYPVKSCK GVPVSEAECT AMGLRSGNLR DRFWLVINQE GNMVTARQEP RLVLISLTCD GDTLTLSAAY TKDLLLPIKT PTTNAVHKCR V HGLEIEGRD CGEATAQWIT SFLKSQPYRL VHFEPHMRPR RPHQIADLFR PKDQIAYSDT SPFLILSEAS LADLNSRLEK KVKATNFRPN IVISGCDVYA EDSWDELLIG DVELKRVMAC SRCILTTVDP DTGVMSRKEP LETLKSYRQC DPSERKLYGK SPLFGQYFVL ENPGTIKVGD PVYLL. It is sometimes possible for the material contained within the vial of "MOCO Sulphurase C-Terminal Domain Containing Protein 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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