Adenylate Cyclase 9 Recombinant Protein | ADCY9 recombinant protein

Recombinant Adenylate Cyclase 9 (ADCY9)

Cat. Num. AAA2029782

• Gene Names: ADCY9; AC9
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: >95%
• Synonyms: Adenylate Cyclase 9; Recombinant Adenylate Cyclase 9 (ADCY9); ADCY9 recombinant protein

• Host: Host: E Coli; Source: Prokaryotic expression
• Purity/Purification: >95%
• Form/Format: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Sequence: The target protein is fused with two N-terminal Tags, His-tag and GST-tag, its sequence is listed below.; TKWLLEWIA GWLPRHCIGA ILVSLPALAV YSHITSEFET NIHVTMFTGS AVLVAVVHYC NFCQLSSWMR SSLATIVGAG LLLLLHISLC QDSSIVMSPL DSAQNFSAQR NPCNSSVLQD GRRPASLIGK ELILTFFLLL LLVWFLNREF EVSYRLHYHG DVEADLHRTK IQSMRDQADWLLRNIIPYHV AEQLKVSQTY SKNHDSGGVI FASIV
• Sequence Length: 1353

• Applicable Applications for ADCY9 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Predicted Molecular Mass: 54.1kDa
• Accurate Molecular Mass (KD): 54kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Expression System: Prokaryotic expression
• Tag: N-terminal His-Tag, GST-tag, S-tag
• Organism Species: Mus musculus (Mouse)
• Fragment: Met1~Asn92
• Usage: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 187951511
• NCBI GeneID: 115
• Molecular Weight: 150,701 Da
• NCBI Official Full Name: Adenylate cyclase 9
• NCBI Official Synonym Full Names: adenylate cyclase 9
• NCBI Official Symbol: ADCY9
• NCBI Official Synonym Symbols: AC9
• NCBI Protein Information: adenylate cyclase type 9
• UniProt Protein Name: Adenylate cyclase type 9
• Protein Family: Adenylate cyclase
• UniProt Gene Name: ADCY9
• UniProt Synonym Gene Names: KIAA0520
• UniProt Entry Name: ADCY9_HUMAN

NCBI Description

Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008]

Uniprot Description

ADCY9: May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Protein type: Transporter; Lyase; Membrane protein, multi-pass; Adenylyl cyclase; Transporter, aquaporin family; Nucleotide Metabolism - purine; Membrane protein, integral; EC 4.6.1.1

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: metal ion binding; ATP binding; adenylate cyclase activity

Biological Process: epidermal growth factor receptor signaling pathway; synaptic transmission; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; phospholipase C activation; water transport; activation of protein kinase A; energy reserve metabolic process; renal water homeostasis; innate immune response; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; signal transduction; G-protein signaling, adenylate cyclase activating pathway; transmembrane transport