Western Blot (WB)
(Western Blot: Sample: Mouse Brain Tissue.)
Rabbit anti-Human Early Growth Response Protein 1 Polyclonal Antibody | anti-EGR1 antibody
Polyclonal Antibody to Early Growth Response Protein 1 (EGR1)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- QQPSLTPLS TIKAFATQSG SQDLKALNTS YQSQLIKPSR MRKYPNRPSK TPPHERPYAC PVESCDRRFS RSDELTRHIR IHTGQKPFQC RICMRNFSRS DHLTTHIRTH TGEKPFACDI CGRKFARSDE RKRHTKIHLR
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Mouse Brain Tissue.)
Western Blot (WB)
(Western Blot: Sample: Mouse Brain Tissue.)
Western Blot (WB)
(Western Blot: Sample: Recombinant EGR1, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant EGR1, Human.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Ovary tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Ovary tissue))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014]
Uniprot Description
EGR1: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation. By growth factors. Belongs to the EGR C2H2-type zinc-finger protein family.
Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 5q31.2
Cellular Component: cytoplasm; nucleoplasm; nucleus
Molecular Function: DNA binding; DNA binding transcription factor activity; double-stranded methylated DNA binding; hemi-methylated DNA-binding; histone acetyltransferase binding; promoter-specific chromatin binding; protein binding; sequence-specific DNA binding; zinc ion binding
Biological Process: BMP signaling pathway; cellular response to gamma radiation; cellular response to heparin; cellular response to interleukin-8; cellular response to mycophenolic acid; glomerular mesangial cell proliferation; negative regulation of canonical Wnt signaling pathway; negative regulation of transcription from RNA polymerase II promoter; positive regulation of chemokine biosynthetic process; positive regulation of gene expression; positive regulation of glomerular metanephric mesangial cell proliferation; positive regulation of hormone biosynthetic process; positive regulation of interleukin-1 beta biosynthetic process; positive regulation of neuron death; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; regulation of apoptosis; regulation of progesterone biosynthetic process; regulation of protein sumoylation; response to glucose stimulus; response to hypoxia; response to insulin stimulus; T cell differentiation; transcription from RNA polymerase II promoter
Research Articles on EGR1
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Product Notes
The EGR1 egr1 (Catalog #AAA2027991) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Early Growth Response Protein 1 (EGR1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Early Growth Response Protein 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 1-5ug/ml Immunocytochemistry in formalin fixed cells: 5-20ug/ml Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml Immunohistochemistry in paraffin section: 5-20ug/ml Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the EGR1 egr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- QQPSLTPLS TIKAFATQSG SQDLKALNTS YQSQLIKPSR MRKYPNRPSK TPPHERPYAC PVESCDRRFS RSDELTRHIR IHTGQKPFQC RICMRNFSRS DHLTTHIRTH TGEKPFACDI CGRKFARSDE RKRHTKIHLR. It is sometimes possible for the material contained within the vial of "Early Growth Response Protein 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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