Western Blot (WB)
(Western Blot: Sample: Lane1: Human Liver Tissue; Lane2: Human 293T Cells; Lane3: Human HepG2 Cells; Lane4: Human Jurkat Cells.)
Rabbit anti-Human Hydroxymethylglutaryl Coenzyme A Synthase Polyclonal Antibody | anti-HMGCS antibody
Polyclonal Antibody to Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS)
Immunocytochemistry in formalin fixed cells: 5-20ug/mL
Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL
Immunohistochemistry in paraffin section: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Lane1: Human Liver Tissue; Lane2: Human 293T Cells; Lane3: Human HepG2 Cells; Lane4: Human Jurkat Cells.)
Western Blot (WB)
(Western Blot: Sample: Lane1: Human Liver Tissue; Lane2: Human 293T Cells; Lane3: Human HepG2 Cells; Lane4: Human Jurkat Cells.)
Western Blot (WB)
(Western Blot: Sample: Recombinant HMGCS, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant HMGCS, Human.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Kidney Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Kidney Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Lung CancerTissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Lung CancerTissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Brain Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Brain Tissue)
NCBI and Uniprot Product Information
Uniprot Description
HMGCS1: This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Belongs to the HMG-CoA synthase family.
Protein type: Amino Acid Metabolism - valine, leucine and isoleucine degradation; Carbohydrate Metabolism - butanoate; EC 2.3.3.10; Lipid Metabolism - synthesis and degradation of ketone bodies; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Transferase
Chromosomal Location of Human Ortholog: 5p12
Cellular Component: cytoplasm; cytosol
Molecular Function: drug binding; hydroxymethylglutaryl-CoA synthase activity; isomerase activity; organic acid binding; protein homodimerization activity
Biological Process: brain development; cellular response to cholesterol; cellular response to follicle-stimulating hormone stimulus; cholesterol biosynthetic process; isoprenoid biosynthetic process; lipid metabolic process; liver development; male gonad development; regulation of cholesterol biosynthetic process; regulation of lipid metabolic process; response to drug; response to low density lipoprotein stimulus; response to low light intensity; response to purine; response to tellurium ion; response to vitamin E
Research Articles on HMGCS
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Product Notes
The HMGCS hmgcs1 (Catalog #AAA2027567) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Hydroxymethylglutaryl Coenzyme A Synthase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-5ug/mL Immunocytochemistry in formalin fixed cells: 5-20ug/mL Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL Immunohistochemistry in paraffin section: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the HMGCS hmgcs1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Hydroxymethylglutaryl Coenzyme A Synthase, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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