Western Blot (WB)
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Mouse anti-Rat Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 Monoclonal Antibody | anti-CEACAM3 antibody
Monoclonal Antibody to Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3)
MGHHHHHHSGSEF- SAQLTVES APTSVAEGAS VLLLVHNLPE NLRAIFWYKG VILFKDLEVA RYVIGTNSSV LGPAHSGRET MYSNGSLLLQ NVTRNDAGFY TLRTLSTDLK AKVVHVQLQV
Western Blot (WB)
(WB Image)
Western Blot (WB)
(WB Image)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013]
Uniprot Description
CEACAM3: Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis. Interacts with S100A9/calprotectin. This interaction is calcium-dependent, but independent of CEACAM3 phosphorylation. CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney. Belongs to the immunoglobulin superfamily. CEA family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell adhesion; Membrane protein, integral; Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: integral to membrane
Research Articles on CEACAM3
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Product Notes
The CEACAM3 ceacam3 (Catalog #AAA2025680) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Researchers should empirically determine the suitability of the CEACAM3 ceacam3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF- SAQLTVES APTSVAEGAS VLLLVHNLPE NLRAIFWYKG VILFKDLEVA RYVIGTNSSV LGPAHSGRET MYSNGSLLLQ NVTRNDAGFY TLRTLSTDLK AKVVHVQLQV. It is sometimes possible for the material contained within the vial of "Carcinoembryonic Antigen Related Cell Adhesion Molecule 3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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