Human MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1) ELISA Kit | MOSC1 elisa kit

Human MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1) ELISA Kit

Cat. Num. AAA2022427

• Gene Names: MARC1; MOSC1
• Reactivity: Human
• Synonyms: MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1); Human MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1) ELISA Kit; Molybdenum Cofactor Sulphurase C-Terminal Domain Containing Protein; Mitochondrial amidoxime-reducing component 1; MOSC1 elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1).; No significant cross-reactivity or interference between MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1) and analogues was observed.
• Sequence Length: 252

• Assay Type: Double-antibody Sandwich
• Samples: Serum, Plasma, Tissue homogenates and Other Biological Fluids
• Detection Range: 0.156-10ng/mL
• Sensitivity: < 0.064ng/mL
• Application: Enzyme-linked immunosorbent assay for Antigen Detection.
• Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1) were tested 20 times on one plate, respectively.
• Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1) were tested on 3 different plates, 8 replicates in each plate.
• CV(%) =: SD/meanX100
• Intra-Assay: CV<10%
• Inter-Assay: CV<12%
• Preparation and Storage: The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. ; To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for MOSC1 elisa kit

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1), biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of MOCO Sulphurase C-Terminal Domain Containing Protein 1 (MOSC1) in the samples is then determined by comparing the O.D. of the samples to the standard curve.

Product Categories/Family for MOSC1 elisa kit

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 119613697
• NCBI GeneID: 64757
• Molecular Weight: 28,439 Da
• NCBI Official Full Name: MOCO sulphurase C-terminal domain containing 1
• NCBI Official Synonym Full Names: mitochondrial amidoxime reducing component 1
• NCBI Official Symbol: MARC1
• NCBI Official Synonym Symbols: MOSC1
• NCBI Protein Information: mitochondrial amidoxime-reducing component 1
• UniProt Protein Name: Mitochondrial amidoxime-reducing component 1
• UniProt Gene Name: MARC1
• UniProt Synonym Gene Names: MOSC1; mARC1; MOSC domain-containing protein 1; Moco sulfurase C-terminal domain-containing protein 1
• UniProt Entry Name: MARC1_HUMAN

Uniprot Description

MOSC1: As a component of an N-hydroxylated prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.-.-.-; Mitochondrial; Oxidoreductase

Chromosomal Location of Human Ortholog: 1q41

Cellular Component: mitochondrial outer membrane; mitochondrion; mitochondrial inner membrane; integral to membrane

Molecular Function: molybdopterin cofactor binding; nitrate reductase activity; molybdenum ion binding; pyridoxal phosphate binding

Biological Process: detoxification of nitrogen compound; nitrate metabolic process