Receptor II For The Fc Region Of Immunoglobulin E (FceRII) Recombinant Protein | FceRII recombinant protein

Recombinant Receptor II For The Fc Region Of Immunoglobulin E (FceRII)

Cat. Num. AAA2011865

• Gene Names: Fcer2a; CD23; Fce2; Fcer2; Ly-42
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Receptor II For The Fc Region Of Immunoglobulin E (FceRII); Recombinant Receptor II For The Fc Region Of Immunoglobulin E (FceRII); FceRII recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with N-terminal His-Tag, its sequence is listed below.; MGHHHHHHSGSEF-LNEKRTASDS LEKLQEEVAK LWIEILISKG TACNICPKNW LHFQQKCYYF GKGSKQWIQA RFACSDLQGR LVSIHSQKEQ DFLMQHINKK DSWIGLQDLN MEGEFVWSDG SPVGYSNWNP GEPNNGGQGE DCVMMRGSGQ WNDAFCRSYL DAWVCEQLAT CEISAPLASV TPTRPTPKSE P
• Sequence Length: 330

• Applicable Applications for FceRII recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Mus musculus (Mouse)
• Expression System: Prokaryotic expression
• Residues: Leu150~Pro330 (Accession # P20693) with N-terminal His-Tag
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

NCBI and Uniprot Product Information

• NCBI GI #: 359339166
• NCBI GeneID: 14128
• NCBI Accession #: NP_001240666.1
• NCBI GenBank Nucleotide #: NM_001253737.1
• UniProt Accession #: P20693; Q61556; Q61557
• Molecular Weight: 22.0kDa
• NCBI Official Full Name: low affinity immunoglobulin epsilon Fc receptor isoform B
• NCBI Official Synonym Full Names: Fc receptor, IgE, low affinity II, alpha polypeptide
• NCBI Official Symbol: Fcer2a
• NCBI Official Synonym Symbols: CD23; Fce2; Fcer2; Ly-42
• NCBI Protein Information: low affinity immunoglobulin epsilon Fc receptor; FC epsilon RII; fc-epsilon-RII; lymphocyte IgE receptor; low-affinity IgE receptor
• UniProt Protein Name: Low affinity immunoglobulin epsilon Fc receptor
• UniProt Gene Name: Fcer2
• UniProt Synonym Gene Names: Fcer2a
• UniProt Entry Name: FCER2_MOUSE

Uniprot Description

FCER2: Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).

Protein type: Membrane protein, integral

Cellular Component: membrane; integral to membrane; plasma membrane; external side of plasma membrane

Molecular Function: metal ion binding; IgE binding; carbohydrate binding

Biological Process: positive regulation of humoral immune response mediated by circulating immunoglobulin; positive regulation of nitric-oxide synthase activity; positive regulation of killing of cells of another organism; positive regulation of nitric-oxide synthase biosynthetic process