Annexin A4 (ANXA4) Recombinant Protein | ANXA4 recombinant protein
Recombinant Annexin A4 (ANXA4)
MGHHHHHHSGSEF-VLVSLSAAGR DEGNYLDDAL MKQDAQELYE AGEKRWGTDE VKFLSILCSR NRNHLLHVFD EYKRISQKDI EQSIKSETSG SFEDALLAIV KCMRSKPSYF AERLYKSMKG LGTDDNTLIR VMVSRAEIDM LDIRASFKRL YGKSLYSFIK GDTSGDYRKV L
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
NCBI and Uniprot Product Information
Uniprot Description
ANXA4: a calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.
Protein type: Lipid-binding; Calcium-binding
Cellular Component: nuclear membrane; cell surface; perinuclear region of cytoplasm; cytoplasm; apical plasma membrane; plasma membrane; vesicle membrane; nucleus
Molecular Function: NF-kappaB binding; identical protein binding; calcium-dependent phospholipid binding; calcium ion binding; calcium-dependent protein binding
Biological Process: regulation of transcription from RNA polymerase II promoter; inhibition of NF-kappaB transcription factor; kidney development