Gene Sequencing (Extract)
Sex Hormone Binding Globulin (SHBG) Recombinant Protein | SHBG recombinant protein
Recombinant Sex Hormone Binding Globulin (SHBG)
Gene Names
Shbg; Abpa
Reactivity
Rattus norvegicus (Rat)
Applications
SDS-Page, Western Blot
Purity
> 97%
Synonyms
Sex Hormone Binding Globulin (SHBG); Recombinant Sex Hormone Binding Globulin (SHBG); SHBG recombinant protein
Host
E.coli
Reactivity
Rattus norvegicus (Rat)
Purity/Purification
> 97%
Form/Format
20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
Concentration
Original Concentration: 300ug/mL (varies by lot)
Sequence
LQPGLFFPP GTHAEFSLQD IPQPHTDPWT FSLELGFKLV DGAGRLLTLG TGTNSSWLTL HLQDQTVVLS SEAEPKLALP LAVGLPLQLK LDVFKVALSQ GPKMEVLSTS LLRLASLWRL WSHPQGHLSL GALPGEDS
Applicable Applications for SHBG recombinant protein
Positive Control; Immunogen; SDS-PAGE; Western Blot (WB).
Source
Prokaryotic expression
Residues
Leu222~Ser358
Tags
N-terminal His Tag
Subcellular Location
Secreted
Traits
Freeze-dried powder
Predicted isoelectric point
5.8
Usage
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 2-8 degree C for one month.
Aliquot and store at -80 degree C for 12 months.
Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Avoid repeated freeze/thaw cycles.
Store at 2-8 degree C for one month.
Aliquot and store at -80 degree C for 12 months.
Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Gene Sequencing (Extract)
Gene Sequencing (Extract)
SDS-Page
SDS-Page
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted Molecular Mass: 21.5kDa
Accurate Molecular Mass: 20kDa as determined by SDS-PAGE reducing conditions.
Accurate Molecular Mass: 20kDa as determined by SDS-PAGE reducing conditions.
NCBI Official Full Name
sex hormone-binding globulin
NCBI Official Synonym Full Names
sex hormone binding globulin
NCBI Official Symbol
Shbg
NCBI Official Synonym Symbols
Abpa
NCBI Protein Information
sex hormone-binding globulin; ABP; SBP; androgen binding protein; sex steroid-binding protein; testis-specific androgen-binding protein; Sex hormone binding globulin or androgen-binding protein (other gene product from ABP gene)
UniProt Protein Name
Sex hormone-binding globulin
Protein Family
UniProt Gene Name
Shbg
UniProt Synonym Gene Names
SHBG; SBP; ABP
UniProt Entry Name
SHBG_RAT
NCBI Description
plays a role in extracellular transport of androgens [RGD, Feb 2006]
Uniprot Description
Function: Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration
By similarity.
Subunit structure: Homodimer.
Subcellular location: Secreted. Note: In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
Tissue specificity: Isoform 2 is only expressed in the liver.
Developmental stage: In the fetal liver, expressed from day 14 to day 17 after conception.
Miscellaneous: A putative trans-splicing which involves HDC and SHBG gene regions produces a fusion protein expressed in fetal liver.
Sequence similarities: Contains 2 laminin G-like domains.
Research Articles on SHBG
Similar Products
Product Notes
The SHBG shbg (Catalog #AAA2010615) is a Recombinant Protein produced from E.coli and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Sex Hormone Binding Globulin (SHBG) reacts with Rattus norvegicus (Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's Sex Hormone Binding Globulin (SHBG) can be used in a range of immunoassay formats including, but not limited to, Positive Control; Immunogen; SDS-PAGE; Western Blot (WB). Researchers should empirically determine the suitability of the SHBG shbg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: LQPGLFFPP GTHAEFSLQD IPQPHTDPWT FSLELGFKLV DGAGRLLTLG TGTNSSWLTL HLQDQTVVLS SEAEPKLALP LAVGLPLQLK LDVFKVALSQ GPKMEVLSTS LLRLASLWRL WSHPQGHLSL GALPGEDS. It is sometimes possible for the material contained within the vial of "Sex Hormone Binding Globulin (SHBG), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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