EIF3K cdna clone
EIF3K
Translation Sequence: MAMFEQMRAN VGKLLKGIDR YNPENLATLE RYVETQAKEN AYDLEANLAV LKLYQFNPAFFQTTVTAQIL LKALTNLPHT DFTLCKCMID QAHQEERPIR QILYLGDLLE TCHFQAFWQALDENMDLLEG ITGFEDSVRK FICHVVGITY QHIDRWLLAE MLGDLSDSQL KVWMSKYGWSADESGQIFIC SQEESIKPKN IVEKIDFDSV SSIMASSQ
NCBI and Uniprot Product Information
NCBI Description
The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 [PubMed 14519125]).[supplied by OMIM, Mar 2008]
Uniprot Description
EIF3K: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Belongs to the eIF-3 subunit K family.
Protein type: Translation initiation; Translation
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: eukaryotic translation initiation factor 3 complex; membrane; cytoplasm; cytosol; nucleus
Molecular Function: protein binding; translation initiation factor activity; ribosome binding
Biological Process: cellular protein metabolic process; translation; translational initiation; gene expression; formation of translation preinitiation complex; regulation of translational initiation
Research Articles on EIF3K
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Product Notes
The EIF3K eif3k (Catalog #AAA200775) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Nucleotide Sequence: ATGGCGATGT TTGAGCAGAT GAGAGCCAAC GTGGGCAAGT TGCTCAAGGG TATCGACAGG TACAATCCTG AGAACCTGGC CACCCTGGAG CGCTATGTAG AGACGCAGGC CAAGGAAAAT GCCTATGATC TGGAAGCCAA CCTGGCTGTC CTGAAGCTGT ACCAGTTCAA CCCAGCCTTC TTTCAGACCA CGGTCACCGC CCAGATCCTG CTGAAGGCCC TCACCAACTT GCCGCACACA GACTTCACCC TGTGCAAGTG CATGATCGAC CAGGCACATC AAGAAGAACG GCCAATCCGA CAGATTTTGT ACCTCGGGGA CCTGCTGGAG ACCTGCCATT TCCAGGCCTT CTGGCAAGCC CTGGATGAAA ACATGGACCT CTTGGAAGGT ATAACTGGCT TTGAAGACTC TGTCCGAAAG TTTATCTGCC ATGTTGTGGG TATCACTTAC CAGCACATTG ACCGCTGGCT GCTGGCCGAG ATGCTCGGGG ATCTGTCGGA CAGCCAGCTA AAGGTGTGGA TGAGCAAATA CGGCTGGAGT GCCGACGAGT CGGGGCAGAT CTTCATCTGT AGCCAAGAAG AGAGCATTAA ACCCAAGAAC ATTGTGGAGA AGATTGACTT TGACAGTGTG TCCAGCATCA TGGCCTCCTC CCAGTAATrans lation Sequence: MAMFEQMRAN VGKLLKGIDR YNPENLATLE RYVETQAKEN AYDLEANLAV LKLYQFNPAF FQTTVTAQIL LKALTNLPHT DFTLCKCMID QAHQEERPIR QILYLGDLLE TCHFQAFWQA LDENMDLLEG ITGFEDSVRK FICHVVGITY QHIDRWLLAE MLGDLSDSQL KVWMSKYGWS ADESGQIFIC SQEESIKPKN IVEKIDFDSV SSIMASSQ. It is sometimes possible for the material contained within the vial of "EIF3K, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.
Precautions
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Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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