Western Blot (WB)
(Western Blot: Sample: Mouse Blood Cells lysate; Primary Ab: 4ug/ml Rabbit Anti-Mouse PECAM1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Rabbit anti-Mouse Platelet/Endothelial Cell Adhesion Molecule (PECAM1) Polyclonal Antibody | anti-PECAM1 antibody
Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)
MGHHHHHHSGSEF-KFEIK PPGMIIEGDQ LHIRCIVQVT HLVQEFTEII IQKDKAIVAT SKQSSEAVYS VMAMVEYSGH YTCKVESNRI SKASSIMVNI TELFPKPKLE FSSSRLDQGE LLDLSCSVSG TPVANFTIQK EETVLSQYQN FSKIAEESDS GEYSCTAGIG KVVKRSGLV
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Mouse Blood Cells lysate; Primary Ab: 4ug/ml Rabbit Anti-Mouse PECAM1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Mouse Blood Cells lysate; Primary Ab: 4ug/ml Rabbit Anti-Mouse PECAM1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded heart tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded heart tissue))
NCBI and Uniprot Product Information
Uniprot Description
PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.
Protein type: Cell adhesion; Cell development/differentiation; Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 11|11 E1
Cellular Component: cell junction; cell periphery; cell surface; external side of plasma membrane; extracellular exosome; extracellular space; integral component of membrane; membrane; membrane raft; plasma membrane; ruffle; smooth muscle contractile fiber
Molecular Function: protein binding; protein phosphatase binding
Biological Process: angiogenesis; cell adhesion; cell-cell adhesion via plasma-membrane adhesion molecules; diapedesis; endothelial cell migration; endothelial cell morphogenesis; leukocyte adhesion; negative regulation of actin filament polymerization; negative regulation of peptidyl-tyrosine phosphorylation; neutrophil extravasation; phagocytosis; positive regulation of cellular extravasation; positive regulation of leukocyte migration; positive regulation of tyrosine phosphorylation of STAT protein; regulation of cell migration; Rho protein signal transduction; wound healing
Research Articles on PECAM1
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Product Notes
The PECAM1 pecam1 (Catalog #AAA2005758) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Platelet/Endothelial Cell Adhesion Molecule (PECAM1) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the PECAM1 pecam1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF-KFEIK PPGMIIEGDQ LHIRCIVQVT HLVQEFTEII IQKDKAIVAT SKQSSEAVYS VMAMVEYSGH YTCKVESNRI SKASSIMVNI TELFPKPKLE FSSSRLDQGE LLDLSCSVSG TPVANFTIQK EETVLSQYQN FSKIAEESDS GEYSCTAGIG KVVKRSGLV. It is sometimes possible for the material contained within the vial of "Platelet/Endothelial Cell Adhesion Molecule (PECAM1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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