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Western Blot (WB) (Western Blot: Sample: Human Raji Cells.)

Rabbit anti-Human V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) Polyclonal Antibody | anti-RELB antibody

Polyclonal Antibody to V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB)

Gene Names
RELB; IREL; I-REL; IMD53; REL-B
Reactivity
Human
Applications
Immunocytochemistry, Immunohistochemistry, ELISA, Western Blot
Purity
Affinity Chromatography
Synonyms
V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB); Polyclonal Antibody; Polyclonal Antibody to V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB); anti-RELB antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against RELB. It has been selected for its ability to recognize RELB in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Concentration
500ug/mL (varies by lot)
Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-DPY NAGSLKNHQE VDMNVVRICF QASYRDQQGQ MRRMDPVLSE PVYDKKSTNT SELRICRINK ESGPCTGGEE LYLLCDKVQK EDISVVFSRA SWEGRADFSQ ADVHRQIAIV FKTPPYEDLE IVEPVTVNVF LQRLTDGVCS EPLPFTYLPR DHDSYGVDKK RKRGMPDVLG ELNSSDPHGI ESKRRKKKPA ILDHFLPNHG SGPFLPPSAL LPDPDFFSGT VSLPGLEPPG GPDLLDDGFA YD
Sequence Length
579
Applicable Applications for anti-RELB antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Immunogen
Recombinant RELB (Asp248~Asp492) expressed in E.coli.
Cross Reactivity
Human
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2059614
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western Blot: Sample: Human Raji Cells.)

Western Blot (WB) (Western Blot: Sample: Human Raji Cells.)

Western Blot (WB)

(Western Blot: Sample: Recombinant RELB, Human.)

Western Blot (WB) (Western Blot: Sample: Recombinant RELB, Human.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Liver Cancer Tissue)

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Liver Cancer Tissue)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Liver cancer Tissue))

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Liver cancer Tissue))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
62,134 Da
NCBI Official Full Name
transcription factor RelB
NCBI Official Synonym Full Names
RELB proto-oncogene, NF-kB subunit
NCBI Official Symbol
RELB
NCBI Official Synonym Symbols
IREL; I-REL; IMD53; REL-B
NCBI Protein Information
transcription factor RelB
UniProt Protein Name
Transcription factor RelB
Protein Family
UniProt Gene Name
RELB

Uniprot Description

RELB: a transcription factor of the nuclear factor-kappaB (NFkB) transcription complex. Stimulates promoter activity in the presence NFkB1/NFkB-p50. Plays role in regulation of apoptosis in hepatocellular carcinoma through activation of downstream target genes. Does not associate with DNA or RelA/NFkB-p65.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: centrosome; cytosol; nucleoplasm; nucleus; protein complex

Molecular Function: chromatin binding; DNA binding transcription factor activity; identical protein binding; protein binding; protein kinase binding; transcription corepressor activity

Biological Process: antigen processing and presentation; cellular response to osmotic stress; circadian regulation of gene expression; I-kappaB kinase/NF-kappaB signaling; inflammatory response; innate immune response; lymphocyte differentiation; myeloid dendritic cell differentiation; negative regulation of interferon-beta production; negative regulation of transcription from RNA polymerase II promoter; NIK/NF-kappaB signaling; positive regulation of transcription from RNA polymerase II promoter; response to cytokine; stimulatory C-type lectin receptor signaling pathway; T-helper 1 cell differentiation; transcription, DNA-dependent

Disease: Immunodeficiency 53

Research Articles on RELB

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Product Notes

The RELB relb (Catalog #AAA2004394) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the RELB relb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-DPY NAGSLKNHQE VDMNVVRICF QASYRDQQGQ MRRMDPVLSE PVYDKKSTNT SELRICRINK ESGPCTGGEE LYLLCDKVQK EDISVVFSRA SWEGRADFSQ ADVHRQIAIV FKTPPYEDLE IVEPVTVNVF LQRLTDGVCS EPLPFTYLPR DHDSYGVDKK RKRGMPDVLG ELNSSDPHGI ESKRRKKKPA ILDHFLPNHG SGPFLPPSAL LPDPDFFSGT VSLPGLEPPG GPDLLDDGFA YD. It is sometimes possible for the material contained within the vial of "V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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