Western Blot (WB)
(Western Blot: Sample: Recombinant CEACAM1, Rat.)
Rabbit anti-Rat Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1) Polyclonal Antibody | anti-CEACAM1 antibody
Polyclonal Antibody to Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1)
MGHHHHHHSGSEF-VT GNNSNPMEGE PFVSLMCEPY TNNTSYLWSR NGESLSEGDR VTFSEGNRTL TLLNVRRTDK GYYECEARNP ATFNRSDPFN LDVIYGPDAP VISPPDIYLH QGSNLNLSCH ADSNPPAQYF WLINEKLQTS SQELFISNIT TNNSGTYACF VNNTVTGLSR TTVKNITVFE PVTQPSIQIT NTTVKELGSV TLTCFSKDTG VSVRWLFNSQ SLQLTDRMTL SQDNSTLRID PIKREDAGDY QCEISNPVSF RIS
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant CEACAM1, Rat.)
Western Blot (WB)
(Western Blot: Sample: Recombinant CEACAM1, Rat.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Intestine Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Intestine Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Stomach Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Stomach Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Liver Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Liver Tissue.)
NCBI and Uniprot Product Information
NCBI Description
glycoprotein component of bile; plays a role in cell adhesion [RGD, Feb 2006]
Uniprot Description
CEACAM1: carcinoembryonic antigen-related cell adhesion molecule 1. A cell-cell adhesion molecule that directly associates with annexin II. Has tumor suppressor activity in prostate carcinoma. Belongs to the immunoglobulin superfamily and the CEA family. Abundantly expressed in epithelia, vessel endothelia, trophoblasts, platelets and neutrophilic granulocytes. Also present in many cell types of the immune system such as B cells, T cells, NK cells, macrophages and dendritic cells. Five alternatively spliced isoforms have been described. Two isoforms are type I membrane proteins, while three are secreted.
Protein type: Cell adhesion; Immunoglobulin superfamily; Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1q21
Cellular Component: adherens junction; apical plasma membrane; basal plasma membrane; brush border membrane; cell junction; cell surface; external side of plasma membrane; extracellular exosome; extracellular space; integral component of membrane; integral component of plasma membrane; intercellular junction; lateral plasma membrane; membrane; microvillus membrane; plasma membrane; T cell receptor complex; transport vesicle
Molecular Function: actin binding; bile acid transmembrane transporter activity; calmodulin binding; filamin binding; granulocyte colony-stimulating factor receptor binding; kinase binding; protein binding; protein dimerization activity; protein homodimerization activity; protein kinase binding; protein phosphatase binding; viral receptor activity; virion binding
Biological Process: bile acid and bile salt transport; blood vessel development; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; cell adhesion; cell-cell adhesion via plasma-membrane adhesion molecules; cell-cell junction organization; cellular response to insulin stimulus; entry of virus into host cell; granulocyte colony-stimulating factor signaling pathway; homophilic cell adhesion; insulin catabolic process; insulin receptor internalization; negative regulation by host of viral process; negative regulation of bone resorption; negative regulation of cytokine production; negative regulation of cytotoxic T cell degranulation; negative regulation of fatty acid biosynthetic process; negative regulation of granulocyte differentiation; negative regulation of hepatocyte proliferation; negative regulation of interleukin-1 production; negative regulation of interleukin-2 production; negative regulation of JNK cascade; negative regulation of lipid biosynthetic process; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; negative regulation of osteoclast differentiation; negative regulation of platelet aggregation; negative regulation of protein kinase activity; negative regulation of T cell mediated cytotoxicity; negative regulation of T cell proliferation; negative regulation of T cell receptor signaling pathway; negative regulation of vascular permeability; Peyer's patch development; positive regulation by host of viral process; positive regulation of CD4-positive, alpha-beta T cell activation; positive regulation of CD4-positive, alpha-beta T cell proliferation; positive regulation of CD8-positive, alpha-beta T cell activation; positive regulation of immunoglobulin secretion; positive regulation of JNK cascade; positive regulation of MAP kinase activity; positive regulation of NFAT protein import into nucleus; positive regulation of T cell proliferation; positive regulation of vasculogenesis; regulation of cell growth; regulation of cell migration; regulation of endothelial cell differentiation; regulation of endothelial cell migration; regulation of epidermal growth factor receptor signaling pathway; regulation of ERK1 and ERK2 cascade; regulation of phosphatidylinositol 3-kinase signaling; signal transduction; wound healing, spreading of cells
Research Articles on CEACAM1
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Product Notes
The CEACAM1 ceacam1 (Catalog #AAA2003528) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the CEACAM1 ceacam1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF-VT GNNSNPMEGE PFVSLMCEPY TNNTSYLWSR NGESLSEGDR VTFSEGNRTL TLLNVRRTDK GYYECEARNP ATFNRSDPFN LDVIYGPDAP VISPPDIYLH QGSNLNLSCH ADSNPPAQYF WLINEKLQTS SQELFISNIT TNNSGTYACF VNNTVTGLSR TTVKNITVFE PVTQPSIQIT NTTVKELGSV TLTCFSKDTG VSVRWLFNSQ SLQLTDRMTL SQDNSTLRID PIKREDAGDY QCEISNPVSF RIS. It is sometimes possible for the material contained within the vial of "Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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