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Western Blot (WB) (Western Blot: Sample: Recombinant CC16, Human.)

Rabbit anti-Human Clara Cell Protein 16 (CC16) Polyclonal Antibody | anti-CC16 antibody

Polyclonal Antibody to Clara Cell Protein 16 (CC16)

Gene Names
SCGB1A1; UGB; UP1; CC10; CC16; CCSP; UP-1; CCPBP
Reactivity
Human
Applications
Immunocytochemistry, Immunohistochemistry, ELISA, Western Blot
Purity
Affinity Chromatography
Synonyms
Clara Cell Protein 16 (CC16); Polyclonal Antibody; Polyclonal Antibody to Clara Cell Protein 16 (CC16); anti-CC16 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against CC16. It has been selected for its ability to recognize CC16 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Concentration
500ug/mL (varies by lot)
Sequence
Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSGSEF-ICPSFQRV IETLLMDTPS SYEAAMELFS PDQDMREAGA QLKKLVDTLP QKPRESIIKL MEKIAQSSLC N
Applicable Applications for anti-CC16 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Immunogen
Recombinant CC16 (Ile23~Asn91) expressed in E.coli.
Cross Reactivity
Human
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2048757
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western Blot: Sample: Recombinant CC16, Human.)

Western Blot (WB) (Western Blot: Sample: Recombinant CC16, Human.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Lung Cancer Tissue.)

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Lung Cancer Tissue.)

Immunohistochemistry (IHC)

(HE staining on IHC-P; Samples: Human Lung Tissue.)

Immunohistochemistry (IHC) (HE staining on IHC-P; Samples: Human Lung Tissue.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
9,994 Da
NCBI Official Full Name
uteroglobin
NCBI Official Synonym Full Names
secretoglobin family 1A member 1
NCBI Official Symbol
SCGB1A1
NCBI Official Synonym Symbols
UGB; UP1; CC10; CC16; CCSP; UP-1; CCPBP
NCBI Protein Information
uteroglobin
UniProt Protein Name
Uteroglobin
UniProt Gene Name
SCGB1A1
UniProt Synonym Gene Names
CC10; CCSP; UGB; CCPBP; CC10; UP-1; UP1; Urine protein 1

NCBI Description

This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. [provided by RefSeq, May 2010]

Uniprot Description

SCGB1A1: Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. Belongs to the secretoglobin family.

Protein type: Cell cycle regulation; Inhibitor; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11q12.3

Cellular Component: extracellular space; nuclear envelope; rough endoplasmic reticulum; secretory granule

Molecular Function: phospholipase A2 inhibitor activity; protein binding

Biological Process: embryo implantation; female pregnancy; negative regulation of catalytic activity; negative regulation of interferon-gamma production; negative regulation of interleukin-13 production; negative regulation of interleukin-4 production; negative regulation of interleukin-5 production; negative regulation of T cell proliferation; negative regulation of transcription from RNA polymerase II promoter; regulation of inflammatory response; regulation of mRNA stability; response to cytokine; response to drug; response to glucocorticoid stimulus; response to lipopolysaccharide; response to ozone; response to silicon dioxide; response to xenobiotic stimulus; signal transduction

Disease: Asthma, Susceptibility To

Research Articles on CC16

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Product Notes

The CC16 scgb1a1 (Catalog #AAA2002206) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Clara Cell Protein 16 (CC16) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Clara Cell Protein 16 (CC16) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the CC16 scgb1a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF-ICPSFQ RV IETLLMDTPS SYEAAMELFS PDQDMREAGA QLKKLVDTLP QKPRESIIKL MEKIAQSSLC N. It is sometimes possible for the material contained within the vial of "Clara Cell Protein 16 (CC16), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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