Rabbit TRICK2 (DR5,TRAIL-R2) Antibody
Anti-TRICK2 (DR5, TRAIL-R2) Antibody
Applications
Immunoblot, Western Blot
Synonyms
TRICK2 (DR5; TRAIL-R2); Anti-TRICK2 (DR5; TRAIL-R2) Antibody; TRICK2; anti-TRICK2 (DR5; TRAIL-R2) antibody
Host
Rabbit
Specificity
TRICK2 (DR5,TRAIL-R2) [Human TRICK2 (DR5, TRAIL-R2)]
This antibody recognizes human TRICK2.
This antibody recognizes human TRICK2.
Form/Format
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Applicable Applications for anti-TRICK2 (DR5,TRAIL-R2) antibody
Immunoblot
Application Notes
Immunoblotting: use at 1:500 dilution. A band of approximately 57 kDa is detected.
Positive control: whole cell lysate from HL60, HeLa, or Jurkat cells.
Positive control: whole cell lysate from HL60, HeLa, or Jurkat cells.
Immunogen
Synthetic peptide corresponding to amino acids 409-427 (LGERLAKQKIEDHLLSSGK, isoform 1) of human TRICK2 precursor conjugated to KLH at the N-terminus. The same sequence is found at amino acids 380-398 in isoform 2.
Stabilizer
None
Preservatives
None. Available on request.
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Related Product Information for anti-TRICK2 (DR5,TRAIL-R2) antibody
Apoptosis is induced by cytokines in the TNF family through their death domain containing receptors. TRICK2 (TRAIL receptor inducer of cell killing 2) is a member of the TNF receptor family and contains the conserved death domain. TRICK2 is expressed at high levels in lymphocytes and spleen cells and in many types of tumor cells. Overexpression of TRICK2 rapidly induces cell death by apoptosis. TRICK2 has been shown to function as a receptor for TRAIL and can inhibit TRAIL-induced killing of lymphocytic cells. Other names for TRICK2 include DR5, Apo2, TRAIL-R2, and KILLER.
Product Categories/Family for anti-TRICK2 (DR5,TRAIL-R2) antibody
References
Screaton,GR et al. (1997) Curr Biol 7: 693-696.
Similar Products
Product Notes
The TRICK2 (DR5,TRAIL-R2) (Catalog #AAA194148) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TRICK2 (DR5,TRAIL-R2) can be used in a range of immunoassay formats including, but not limited to, Immunoblot. Immunoblotting: use at 1:500 dilution. A band of approximately 57 kDa is detected. Positive control: whole cell lysate from HL60, HeLa, or Jurkat cells. Researchers should empirically determine the suitability of the TRICK2 (DR5,TRAIL-R2) for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRICK2 (DR5,TRAIL-R2), Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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