Rabbit MPP1/KIF20B Polyclonal Antibody | anti-MPP1/KIF20B antibody
Anti-MPP1/KIF20B Antibody
Gene Names
KIF20B; CT90; MPP1; KRMP1; MPP-1; MPHOSPH1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Immunogen Affinity Purified
Synonyms
MPP1/KIF20B; Polyclonal Antibody; Anti-MPP1/KIF20B Antibody; Kinesin-like protein KIF20B; kinesin family member 20B; Cancer/testis antigen 90; CT90; Kinesin family member 20B; Kinesin-related motor interacting with PIN1; M-phase phosphoprotein 1; MPP1; KIF20B; KRMP1; anti-MPP1/KIF20B antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
No cross reactivity with other proteins.
Purity/Purification
Immunogen Affinity Purified
Form/Format
Lyophilized
Sequence Length
1820
Applicable Applications for anti-MPP1/KIF20B antibody
Western Blot (WB), Direct ELISA (EIA)
Application Notes
WB: 0.1-0.5ug/ml
Direct ELISA: 0.1-0.5ug/ml
Direct ELISA: 0.1-0.5ug/ml
Immunogen
E Coli-derived human MPP1/KIF20B recombinant protein (Position: A19-D231).
Contents
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Relevant Detection Systems
Relevant Detection Systems
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500mug/ml.
Relevant Detection Systems
Relevant Detection Systems
Relevant Detection Systems
We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (MBS176460) for Western blot.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Related Product Information for anti-MPP1/KIF20B antibody
Description: Rabbit IgG polyclonal antibody for MPP1/KIF20B detection. Tested with WB, Direct ELISA in Human; Mouse; Rat.
Background: Kinesin-like protein KIF20B is a protein that in humans is encoded by the KIF20B gene. The MPP1 gene is previously labeled as KIF20B. Palmitoylated membrane protein 1 is the prototype of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 1 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction.
Background: Kinesin-like protein KIF20B is a protein that in humans is encoded by the KIF20B gene. The MPP1 gene is previously labeled as KIF20B. Palmitoylated membrane protein 1 is the prototype of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 1 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction.
References
1. Kamimoto, T., Zama, T., Aoki, R., Muro, Y., Hagiwara, M. Identification of a novel kinesin-related protein, KRMP1, as a target for mitotic peptidyl-prolyl isomerase Pin1. J. Biol. Chem. 276: 37520-37528, 2001. 2. Matsumoto-Taniura, N., Pirollet, F., Monroe, R., Gerace, L., Westendorf, J. M. Identification of novel M phase phosphoproteins by expression cloning. Molec. Biol. Cell 7: 1455-1469, 1996. 3. Westendorf, J. M., Rao, P. N., Gerace, L. Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope. Proc. Nat. Acad. Sci. 91: 714-718, 1994.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
kinesin-like protein KIF20B isoform 1
NCBI Official Synonym Full Names
kinesin family member 20B
NCBI Official Symbol
KIF20B
NCBI Official Synonym Symbols
CT90; MPP1; KRMP1; MPP-1; MPHOSPH1
NCBI Protein Information
kinesin-like protein KIF20B
UniProt Protein Name
Kinesin-like protein KIF20B
UniProt Gene Name
KIF20B
UniProt Synonym Gene Names
MPP1
Uniprot Description
Plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth (). Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).
Research Articles on MPP1/KIF20B
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Product Notes
The MPP1/KIF20B kif20b (Catalog #AAA1752543) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MPP1/KIF20B Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MPP1/KIF20B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Direct ELISA (EIA). WB: 0.1-0.5ug/ml Direct ELISA: 0.1-0.5ug/ml. Researchers should empirically determine the suitability of the MPP1/KIF20B kif20b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MPP1/KIF20B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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