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Cancer Antigen 125 Active Protein | MUC16 active protein

Cancer Antigen 125 (CA-125), Human

Gene Names
MUC16; CA125
Purity
> 95% (SDS-PAGE)
Synonyms
Cancer Antigen 125; Cancer Antigen 125 (CA-125); Human; CA-125; Carbohydrate Antigen 125; Mucin-16; MUC16 active protein
Ordering
For Research Use Only!
Purity/Purification
> 95% (SDS-PAGE)
Form/Format
Solution in phosphate buffered saline pH 7.4 with 3% sucrose and 0.05% sodium azide
Sequence Length
22,152
Source
Human Ascites Fluid,adenocarcinoma
Appearance
Clear and colorless
Activity
380 kU/mL (EIA)
Handling
Handle as a potentially hazardous substance.
Recovery
Microfuge the vial before drawing from container.
Preparation and Storage
Store at -20°C.
Avoid freeze/thaws.
Shipping: Ships with Dry Ice.
Related Product Information for MUC16 active protein
MyBioSource is the leading supplier of Cancer Antigen 125 (CA-125, MUCIN 16) for ovarian cancer research and biomarkers for manufacturing.

Custom preparations, technical support, bulk quantities and aliquoting available.

Cancer Antigen 125 (CA125) is a surface antigen associated with epithelial ovarian cancer. In serum, CA125 is associated with a high molecular weight glycoprotein. Published studies have indicated that elevated serum CA125 levels can be found in individuals with serious endometroid, clear-cell and undifferentiated ovarian carcinoma.

Associated Cancer Types: Ovarian Cancer Endometrial Cancer Fallopian Tube Cancer Lung Cancer Breast Cancer Gastrointestinal Cancer

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Mucin-16
NCBI Official Synonym Full Names
mucin 16, cell surface associated
NCBI Official Symbol
MUC16
NCBI Official Synonym Symbols
CA125
NCBI Protein Information
mucin-16; CA125 ovarian cancer antigen; ovarian carcinoma antigen CA125; ovarian cancer-related tumor marker CA125
UniProt Protein Name
Mucin-16
Protein Family
UniProt Gene Name
MUC16
UniProt Synonym Gene Names
CA125; MUC-16; CA-125
UniProt Entry Name
MUC16_HUMAN

Uniprot Description

MUC16: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.

Protein type: Cell adhesion; Membrane protein, peripheral; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: extracellular space; extrinsic to membrane; Golgi lumen; plasma membrane; integral to membrane; vesicle

Molecular Function: protein binding

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; cell adhesion; post-translational protein modification

Research Articles on MUC16

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Product Notes

The MUC16 muc16 (Catalog #AAA173332) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Cancer Antigen 125, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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