Human Hydroxyacid oxidase 1, HAO1 ELISA Kit | HAO1 elisa kit
Human Hydroxyacid oxidase 1, HAO1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008]
Uniprot Description
HAO1: Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2- hydroxy octanoate. Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
Protein type: EC 1.1.3.15; Oxidoreductase; Carbohydrate Metabolism - glyoxylate and dicarboxylate
Chromosomal Location of Human Ortholog: 20p12
Cellular Component: peroxisomal matrix; peroxisome
Molecular Function: glycolate oxidase activity; FMN binding; glyoxylate oxidase activity; (S)-2-hydroxy-acid oxidase activity; receptor binding
Biological Process: glyoxylate metabolic process; response to oxidative stress; glycolate catabolic process; fatty acid alpha-oxidation
Research Articles on HAO1
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Product Notes
The Human HAO1 hao1 (Catalog #AAA1606348) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA1606348 ELISA Kit recognizes Human HAO1. It is sometimes possible for the material contained within the vial of "Hydroxyacid oxidase 1, HAO1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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