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Tnnt2 recombinant protein

Recombinant Rat Tnnt2 protein, C-His Tag

Gene Names
Tnnt2; Ctt; CTTG; Tnnt3; RATCTTG
Purity
>90% as determined by SDS-PAGE
Synonyms
Tnnt2; Recombinant Rat Tnnt2 protein; C-His Tag; TnTc; Cardiac muscle troponin T; cTnT; Tnnt2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
>90% as determined by SDS-PAGE
Form/Format
Lyophilized. Lyophilized from PBS pH 7.4, 0.2% NLS, 5% Trehalose, 5% Mannose, 1mM EDTA.
Source
Rat
Construction
A DNA sequence encoding the Rat Tnnt2 (Met1-Lys299) was fused with the C-terminal His Tag
Preparation and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for ~12 months from the date of receipt.
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
In general, proteins are provided as lyophilized powder. They are shipped out with blue ice unless customers require otherwise
Product Categories/Family for Tnnt2 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,730 Da
NCBI Official Full Name
troponin T, cardiac muscle
NCBI Official Synonym Full Names
troponin T type 2 (cardiac)
NCBI Official Symbol
Tnnt2
NCBI Official Synonym Symbols
Ctt; CTTG; Tnnt3; RATCTTG
NCBI Protein Information
troponin T, cardiac muscle; cTnT; tnTc; Troponin T cardiac; cardiac troponin T2; troponin T2, cardiac; cardiac muscle troponin T
UniProt Protein Name
Troponin T, cardiac muscle
Protein Family
UniProt Gene Name
Tnnt2
UniProt Entry Name
TNNT2_RAT

NCBI Description

tropomyosin-binding subunit of troponin; confers calcium-sensitivy to actinomysin ATPase activity in striated muscle [RGD]

Uniprot Description

TNNT2: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart. Belongs to the troponin T family. 11 isoforms of the human protein are produced by alternative splicing.

Protein type: Motor; Motility/polarity/chemotaxis

Cellular Component: sarcomere; troponin complex; myofibril; cytoplasm; striated muscle thin filament

Molecular Function: protein binding, bridging; troponin C binding; structural constituent of cytoskeleton; troponin I binding; ATPase activity; tropomyosin binding; actin binding

Biological Process: actin crosslink formation; protein heterooligomerization; regulation of muscle contraction; atrial cardiac muscle morphogenesis; metabolic process; heart development; regulation of muscle filament sliding speed; sarcomere organization; regulation of heart contraction; muscle filament sliding; muscle contraction; positive regulation of ATPase activity; ventricular cardiac muscle morphogenesis; response to calcium ion; negative regulation of ATPase activity; cardiac muscle contraction

Research Articles on Tnnt2

Similar Products

Product Notes

The Tnnt2 tnnt2 (Catalog #AAA157693) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Tnnt2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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