Rabbit ETV4 Polyclonal Antibody | anti-ETV4 antibody
ETV4 Antibody
Gene Names
ETV4; E1AF; PEA3; E1A-F; PEAS3
Reactivity
Human, Mouse, RatPredicted: Zebrafish (72%)
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column.
Synonyms
ETV4; Polyclonal Antibody; ETV4 Antibody; ETS variant 4; E1AF; PEA3; E1A-F; PEAS3; ETS translocation varinat 4; anti-ETV4 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Predicted: Zebrafish (72%)
Predicted: Zebrafish (72%)
Clonality
Polyclonal
Isotype
IgG
Specificity
At least three isoforms of ETV4 are known to exist. This antibody will only detect the two longest isoforms.
Purity/Purification
Affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
484
Applicable Applications for anti-ETV4 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Western blot at 1 - 2 mug/mL.
Conjugate
Unconjugated
Immunogen
ETV4 antibody was raised against a peptide corresponding to 19 amino acids near the amino terminus of human ETV4.
Buffer
ETV4 Antibody is supplied in PBS containing 0.02% sodium azide.
Species
Human
Preparation and Storage
Store at 4 degree C for three months and -20 degree C, stable for up to one year.
As with all antibodies care should be taken to avoid repeated freeze thaw cycles.
Antibodies should not be exposed to prolonged high temperatures.
As with all antibodies care should be taken to avoid repeated freeze thaw cycles.
Antibodies should not be exposed to prolonged high temperatures.
Related Product Information for anti-ETV4 antibody
ETV4 Antibody: ETV4, along with the related proteins ETV1 and ETV5, form the PEA3 subfamily of the E26 transformation-specific (ETS) transcription factor family (1). ETV4 is thought to play roles in embryonic kidney development and fertility (2,3), and is also thought to be an oncoprotein in multiple cancers (4).
Product Categories/Family for anti-ETV4 antibody
References
1. Xin JH, Cowie A, LAchance P, et al. Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells. Genes Dev. 1992; 6:481-96. 2. Lu BC, Cebrian C, Chi X, et al. Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis. Nat. Genet. 2009; 41:1295-302. 3. Laing MA, Coonrod S, Hinton BT, et al. Male sexual dysfunction in mice bearing targeted mutant alleles of the PEA3 ets gene. Mol. Cell. Biol. 2000; 20:9337-45. 4. Oh S, Shin S, and Janknecht R. ETV1, 4 and 5: An oncogenic subfamily of ETS transcription factors. Biochim. Biophys. Acta 2012: 1826:1-12.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 53 kDa
Observed: 53 kDa
Observed: 53 kDa
NCBI Official Full Name
ETS translocation variant 4 isoform 1
NCBI Official Synonym Full Names
ETS variant 4
NCBI Official Symbol
ETV4
NCBI Official Synonym Symbols
E1AF; PEA3; E1A-F; PEAS3
NCBI Protein Information
ETS translocation variant 4
UniProt Protein Name
ETS translocation variant 4
Protein Family
UniProt Gene Name
ETV4
UniProt Synonym Gene Names
E1AF; PEA3; Protein PEA3
Uniprot Description
ETV4: Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'. Belongs to the ETS family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 17q21.31
Cellular Component: nucleolus; nucleoplasm; nucleus
Molecular Function: protein binding
Biological Process: cell differentiation; positive regulation of transcription from RNA polymerase II promoter
Research Articles on ETV4
Similar Products
Product Notes
The ETV4 etv4 (Catalog #AAA154451) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ETV4 Antibody reacts with Human, Mouse, Rat Predicted: Zebrafish (72%) and may cross-react with other species as described in the data sheet. AAA Biotech's ETV4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the ETV4 etv4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ETV4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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