NELF blocking peptide
NELF Peptide
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is involved in guidance of olfactory axon projections and migration of luteinizing hormone-releasing hormone neurons. Defects in this gene are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
Uniprot Description
NSMF: Couples NMDA receptor signaling to the nucleus. Influences outgrowth of olfactory axons and migration of LHRH neurons. Defects in NELF may be associated with idiopathic hypogonadotropic hypogonadism (IHH). IHH is defined as a deficiency of the pituitary secretion of follicle-stimulating hormone and luteinizing hormone, which results in the impairment of pubertal maturation and of reproductive function. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 9q34.3
Cellular Component: cortical cytoskeleton; neuron projection; nuclear membrane; nuclear matrix; postsynaptic density; dendrite; perikaryon; nuclear envelope; nucleoplasm; postsynaptic membrane; membrane; cytoplasm; synapse; nucleus; cell junction
Molecular Function: calcium-dependent protein binding
Biological Process: regulation of dendrite morphogenesis; regulation of neuron apoptosis; positive regulation of protein amino acid dephosphorylation; regulation of neuronal synaptic plasticity
Disease: Hypogonadotropic Hypogonadism 9 With Or Without Anosmia
Research Articles on NELF
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Product Notes
The NELF nsmf (Catalog #AAA153850) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's NELF can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). NELFpeptide is used for blocking the activity of NELF antibody. Researchers should empirically determine the suitability of the NELF nsmf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NELF, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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