Irak2 blocking peptide
IRAK2 Peptide
NCBI and Uniprot Product Information
Uniprot Description
IRAK2: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Interacts with MYD88. IL-1 stimulation leads to the formation of a signaling complex which dissociates from the IL-1 receptor following the binding of PELI1. Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, TKL; TKL group; IRAK family
Cellular Component: interleukin-1 receptor complex; cytoplasm; nucleus
Molecular Function: protein serine/threonine kinase activity; protein binding; protein homodimerization activity; protein heterodimerization activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; ATP binding; protein kinase activity
Biological Process: regulation of apoptosis; inhibition of NF-kappaB transcription factor; negative regulation of transcription factor activity; protein amino acid autophosphorylation; activation of NF-kappaB-inducing kinase; lipopolysaccharide-mediated signaling pathway; toll-like receptor signaling pathway; regulation of cytokine and chemokine mediated signaling pathway; signal transduction; protein amino acid phosphorylation; activation of NF-kappaB transcription factor
Research Articles on Irak2
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Product Notes
The Irak2 irak2 (Catalog #AAA152293) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IRAK2 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). IRAK2 peptide is used for blocking the activity of IRAK2 antibody. Researchers should empirically determine the suitability of the Irak2 irak2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IRAK2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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