Western Blot (WB)
(Western blot analysis of CHORDC1 in 293 cell lysate with CHORDC1 antibody at (A) 1 and (B) 2 μg/mL.)
Rabbit CHORDC1 Polyclonal Antibody | anti-CHORDC1 antibody
CHORDC1 Antibody
Gene Names
CHORDC1; CHP1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunocytochemistry, Immunofluorescence
Purity
CHORDC1 Antibody is affinity chromatography purified via peptide column.
Synonyms
CHORDC1; Polyclonal Antibody; CHORDC1 Antibody; CHP1; Cysteine and histidine-rich domain-containing protein 1; CHORD domain-containing protein 1; CHORD-containing protein 1; cysteine and histidine-rich domain (CHORD)-containing 1; anti-CHORDC1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
CHORDC1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
332
Applicable Applications for anti-CHORDC1 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes
CHORDC1 antibody can be used for detection of CHORDC1 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunocytochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
CHORDC1 antibody was raised against a 21 amino acid synthetic peptide near the amino terminus of human CHORDC1.
Buffer
CHORDC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
CHORDC1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of CHORDC1 in 293 cell lysate with CHORDC1 antibody at (A) 1 and (B) 2 μg/mL.)
Western Blot (WB)
(Western blot analysis of CHORDC1 in 293 cell lysate with CHORDC1 antibody at (A) 1 and (B) 2 μg/mL.)
Immunocytochemistry (IHC)
(Immunocytochemistry of CHORDC1 in 293 cells with CHORDC1 antibody at 2.5 μg/mL.)
Immunocytochemistry (IHC)
(Immunocytochemistry of CHORDC1 in 293 cells with CHORDC1 antibody at 2.5 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of CHORDC1 in 293 cells with CHORDC1 antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of CHORDC1 in 293 cells with CHORDC1 antibody at 20 μg/mL.)
Related Product Information for anti-CHORDC1 antibody
CHORDC1 Antibody: The cysteine and histidine-rich domain (CHORD)-containing protein (CHORDC1) is a member of a highly conserved protein family that contains the plant protein RAR1 and the mammalian protein melusin. In mammals, CHORDC1 is an ADP-dependent HSP90-interacting protein, and this interaction is dependent on the ability of HSP90 to bind nucleotides. Recent experiments indicate that CHORDC1 mRNA is diurnally regulated in mouse hypothalamus, and that this regulation alters during development, suggesting that CHORDC1 may play a role in circadian mechanisms in the mammalian brain.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35,286 Da
NCBI Official Full Name
cysteine and histidine-rich domain-containing protein 1 isoform a
NCBI Official Synonym Full Names
cysteine and histidine-rich domain (CHORD) containing 1
NCBI Official Symbol
CHORDC1
NCBI Official Synonym Symbols
CHP1
NCBI Protein Information
cysteine and histidine-rich domain-containing protein 1; CHP-1; protein morgana; CHORD-containing protein 1; chord domain-containing protein 1; cysteine and histidine-rich domain (CHORD)-containing 1; cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
UniProt Protein Name
Cysteine and histidine-rich domain-containing protein 1
Protein Family
UniProt Gene Name
CHORDC1
UniProt Synonym Gene Names
CHP1; CHORD-containing protein 1; CHP-1
UniProt Entry Name
CHRD1_HUMAN
Uniprot Description
CHORDC1: Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Calcium-binding
Chromosomal Location of Human Ortholog: 11q14.3
Molecular Function: protein binding; zinc ion binding; Hsp90 protein binding
Research Articles on CHORDC1
Similar Products
Product Notes
The CHORDC1 chordc1 (Catalog #AAA150533) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CHORDC1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CHORDC1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF). CHORDC1 antibody can be used for detection of CHORDC1 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunocytochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the CHORDC1 chordc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CHORDC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
