Western Blot (WB)
(Western blot analysis of ATOH8 in A-20 cell lysate with ATOH8 antibody at (A) 1 and (B) 2 μg/mL.)
Rabbit ATOH8 Polyclonal Antibody | anti-ATOH8 antibody
ATOH8 Antibody
Gene Names
ATOH8; HATH6; bHLHa21
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
ATOH8 Antibody is affinity chromatography purified via peptide column.
Synonyms
ATOH8; Polyclonal Antibody; ATOH8 Antibody; HATH6; bHLHa21; ATH6; BHLHA21; Protein atonal homolog 8; Class A basic helix-loop-helix protein 21; atonal homolog 8 (Drosophila); anti-ATOH8 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
ATOH8 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
321
Applicable Applications for anti-ATOH8 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ATOH8 antibody can be used for detection of ATOH8 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL.
Conjugate
Unconjugated
Immunogen
ATOH8 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ATOH8.
Buffer
ATOH8 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
ATOH8 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of ATOH8 in A-20 cell lysate with ATOH8 antibody at (A) 1 and (B) 2 μg/mL.)
Western Blot (WB)
(Western blot analysis of ATOH8 in A-20 cell lysate with ATOH8 antibody at (A) 1 and (B) 2 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of ATOH8 in mouse brain tissue with ATOH8 antibody at 5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of ATOH8 in mouse brain tissue with ATOH8 antibody at 5 μg/mL.)
Related Product Information for anti-ATOH8 antibody
ATOH8 Antibody: Basic helix-loop-helix (bHLH) transcription factors play important roles in differentiation processes during embryonic development of vertebrates. ATOH8 (MATH6) is a tissue-restricted member of the atonal superfamily of bHLH transcription factors that exhibits 43-57% identity in the bHLH domain with other mammalian atonal paralogs including the NeuroD and Neurogenin factors. In the mouse, ATOH8 has been implicated in the specification and differentiation of neuronal cell lineages in the brain and may also participate in kidney development. Recent studies show that ATOH8 is a novel component of the pancreatic transcriptional network during embryonic development and suggest a potential role as a modulator of the differentiation program initiated by the pro-endocrine factor Neurog3. It is indispensable for early embryonic development, suggesting a more widespread function for this factor in tissue-specific differentiation processes that are dependent on class II bHLH genes.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,801 Da
NCBI Official Full Name
protein atonal homolog 8
NCBI Official Synonym Full Names
atonal homolog 8 (Drosophila)
NCBI Official Symbol
ATOH8
NCBI Official Synonym Symbols
HATH6; bHLHa21
NCBI Protein Information
protein atonal homolog 8; atonal homolog 6; helix-loop-helix protein hATH-6; class A basic helix-loop-helix protein 21; basic helix loop helix transcription factor 6; basic helix-loop-helix transcription factor 6
UniProt Protein Name
Protein atonal homolog 8
Protein Family
UniProt Gene Name
ATOH8
UniProt Synonym Gene Names
ATH6; BHLHA21; bHLHa21; hATH6
UniProt Entry Name
ATOH8_HUMAN
Uniprot Description
ATOH8: Putative transcription factor. May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 2p11.2
Cellular Component: nucleus
Molecular Function: protein dimerization activity; DNA binding
Biological Process: nervous system development; transcription, DNA-dependent; regulation of transcription, DNA-dependent; cell differentiation
Research Articles on ATOH8
Similar Products
Product Notes
The ATOH8 atoh8 (Catalog #AAA150120) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATOH8 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ATOH8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ATOH8 antibody can be used for detection of ATOH8 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. Researchers should empirically determine the suitability of the ATOH8 atoh8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATOH8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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