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Western Blot (WB) (Western blotAll lanes: Cerberus antibody at 2ug/mlLane 1:Hela whole cell lysateLane 2:Rat kidney tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 30kDaObserved band size: 30kDa)

Rabbit anti-Human, Rat Cerberus Polyclonal Antibody | anti-CER1 antibody

Rabbit anti-human Cerberus polyclonal Antibody(CER1)

Gene Names
CER1; DAND4
Reactivity
Human, Rat
Applications
ELISA, Western Blot
Purity
Antigen Affinity Purified
Synonyms
Cerberus; Polyclonal Antibody; Rabbit anti-human Cerberus polyclonal Antibody(CER1); Cerberus-related protein; DAN domain family member 4; CER1; DAND4; anti-CER1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
267
Applicable Applications for anti-CER1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Recommended dilution: WB:1:500-2000
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Cerberus protein (18-267aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-15131 / sc-15132 / sc-15134
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: Cerberus antibody at 2ug/mlLane 1:Hela whole cell lysateLane 2:Rat kidney tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 30kDaObserved band size: 30kDa)

Western Blot (WB) (Western blotAll lanes: Cerberus antibody at 2ug/mlLane 1:Hela whole cell lysateLane 2:Rat kidney tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 30kDaObserved band size: 30kDa)
Related Product Information for anti-CER1 antibody
Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30,084 Da
NCBI Official Full Name
cerberus
NCBI Official Synonym Full Names
cerberus 1, DAN family BMP antagonist
NCBI Official Symbol
CER1
NCBI Official Synonym Symbols
DAND4
NCBI Protein Information
cerberus
UniProt Protein Name
Cerberus
Protein Family
UniProt Gene Name
CER1
UniProt Synonym Gene Names
DAND4
UniProt Entry Name
CER1_HUMAN

NCBI Description

This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008]

Uniprot Description

CER1: Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak. Belongs to the DAN family.

Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 9p23-p22

Cellular Component: extracellular region; extracellular space

Molecular Function: cytokine activity; morphogen activity; protein homodimerization activity

Biological Process: anterior/posterior axis specification; anterior/posterior pattern formation; BMP signaling pathway; bone mineralization; cell migration involved in gastrulation; determination of dorsal identity; gastrulation; negative regulation of activin receptor signaling pathway; negative regulation of BMP signaling pathway; negative regulation of cell proliferation; negative regulation of Wnt receptor signaling pathway; nervous system development; ureteric bud development

Research Articles on CER1

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Product Notes

The CER1 cer1 (Catalog #AAA1493973) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Cerberus polyclonal Antibody(CER1) reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Cerberus can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Recommended dilution: WB:1:500-2000. Researchers should empirically determine the suitability of the CER1 cer1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cerberus, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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