RNA-binding protein 40 (RNPC3) Recombinant Protein | RNPC3 recombinant protein

Recombinant Human RNA-binding protein 40 (RNPC3)

Cat. Num. AAA1477832

• Gene Names: RNPC3; RNP; RBM40; SNRNP65
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: RNA-binding protein 40 (RNPC3); Recombinant Human RNA-binding protein 40 (RNPC3); RNPC3 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-517 aa; Full Length
• Sequence: MAAPEQPLAISRGCTSSSSLSPPRGDRTLLVRHLPAELTAEEKEDLLKYFGAQSVRVLSDKGRLKHTAFATFPNEKAAIKALTRLHQLKLLGHTLVVEFAKEQDRVHSPCPTSGSEKKKRSDDPVEDDKEKKELGYLTVENGIAPNHGLTFPLNSCLKYMYPPPSSTILANIVNALASVPKFYVQVLHLMNKMNLPTPFGPITARPPMYEDYMPLHAPLPPTSPQPPEEPPLPDEDEELSSEESEYESTDDEDRQRMNKLMELANLQPKRPKTIKQRHVRKKRKIKDMLNTPLCPSHSSLHPVLLPSDVFDQPQPVGNKRIEFHISTDMPAAFKKDLEKEQNCEEKNHDLPATEVDASNIGFGKIFPKPNLDITEEIKEDSDEMPSECISRRELEKGRISREEMETLSVFRSYEPGEPNCRIYVKNLAKHVQEKDLKYIFGRYVDFSSETQRIMFDIRLMKEGRMKGQAFIGLPNEKAAAKALKEANGYVLFGKPMVVQFARSARPKQDPKEGKRKC
• Sequence Length: 517

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for RNPC3 recombinant protein

Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.

NCBI and Uniprot Product Information

• NCBI GI #: 40538732
• NCBI GeneID: 55599
• NCBI Accession #: NP_060089.1
• NCBI GenBank Nucleotide #: NM_017619.3
• UniProt Accession #: Q96LT9; Q5TZ87; Q96FK7; Q96JI8; Q9NSU7; Q9NXX2; A8K1C9; D3DT74
• Molecular Weight: 58,488 Da
• NCBI Official Full Name: RNA-binding protein 40
• NCBI Official Synonym Full Names: RNA binding region (RNP1, RRM) containing 3
• NCBI Official Symbol: RNPC3
• NCBI Official Synonym Symbols: RNP; RBM40; SNRNP65
• NCBI Protein Information: RNA-binding protein 40
• UniProt Protein Name: RNA-binding protein 40
• Protein Family: RNA-binding protein
• UniProt Gene Name: RNPC3
• UniProt Synonym Gene Names: KIAA1839; RBM40; RNP; U11/U12 snRNP 65 kDa protein; U11/U12-65K

NCBI Description

Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome. [provided by RefSeq, Jul 2008]

Uniprot Description

Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m7G-capped U12 snRNA.