Cell division cycle protein 23 homolog (Cdc23) Recombinant Protein | Cdc23 recombinant protein

Recombinant Mouse Cell division cycle protein 23 homolog (Cdc23)

Cat. Num. AAA1470877

• Gene Names: Cdc23; 6030435O18; D18Ertd243e
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Cell division cycle protein 23 homolog (Cdc23); Recombinant Mouse Cell division cycle protein 23 homolog (Cdc23); Cdc23 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 2-597, Full length protein
• Sequence: AANSSVVSVAAAATAVPGVSTVADFSDLQEIKKQLLLIAGLTRERGLLHSSKWSAELAFSLPALPLSELQPPPPLTEEDAQDVDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSRKHQARGLDGFGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQHLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKKALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCGETVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLRNQGETPTSDTPGTFFLPASLSANNTPTRRVSPLNLSSVTP
• Sequence Length: 596

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Cdc23 recombinant protein

This protein shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2
M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

NCBI and Uniprot Product Information

• NCBI GI #: 30387632
• NCBI GeneID: 52563
• NCBI Accession #: NP_848124.1
• NCBI GenBank Nucleotide #: NM_178347.4
• UniProt Accession #: Q8BGZ4; Q6PD06; Q8C0F1
• Molecular Weight: 55,810 Da
• NCBI Official Full Name: cell division cycle protein 23 homolog
• NCBI Official Synonym Full Names: CDC23 cell division cycle 23
• NCBI Official Symbol: Cdc23
• NCBI Official Synonym Symbols: 6030435O18; D18Ertd243e
• NCBI Protein Information: cell division cycle protein 23 homolog
• UniProt Protein Name: Cell division cycle protein 23 homolog
• Protein Family: Cell division cycle protein
• UniProt Gene Name: Cdc23
• UniProt Synonym Gene Names: Anapc8; APC8

Uniprot Description

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains ().