EGF-containing fibulin-like extracellular matrix protein 1 (Efemp1) Recombinant Protein | Efemp1 recombinant protein
Recombinant Mouse EGF-containing fibulin-like extracellular matrix protein 1 (Efemp1)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
EGF-containing fibulin-like extracellular matrix protein 1 (Efemp1); Recombinant Mouse EGF-containing fibulin-like extracellular matrix protein 1 (Efemp1); Efemp1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
18-493. Full Length of Mature Protein
Sequence
QYTEETITYTQCTDGYEWDPIRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEHPQQETPAAEASSGATTGTVAARSMATSGVVPGGGFMASATAVAGPEVQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTSGTHNCRTDQVCINLRGSFTCQCLPGYQKRGEQCVDIDECTVPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYEVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDHYVLTSENRCVCPVSNTMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATMIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREYIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSFQNWPHYRSP
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Efemp1 recombinant protein
This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55 kDa
NCBI Official Full Name
EGF-containing fibulin-like extracellular matrix protein 1
NCBI Official Synonym Full Names
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
NCBI Official Symbol
Efemp1
NCBI Protein Information
EGF-containing fibulin-like extracellular matrix protein 1
UniProt Protein Name
EGF-containing fibulin-like extracellular matrix protein 1
Protein Family
UniProt Gene Name
Efemp1
UniProt Synonym Gene Names
Fbln3; FIBL-3
Uniprot Description
Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth ().
Research Articles on Efemp1
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Product Notes
The Efemp1 efemp1 (Catalog #AAA1470386) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 18-493. Full Length of Mature Protein. The amino acid sequence is listed below: QYTEETITYT QCTDGYEWDP IRQQCKDIDE CDIVPDACKG GMKCVNHYGG YLCLPKTAQI IVNNEHPQQE TPAAEASSGA TTGTVAARSM ATSGVVPGGG FMASATAVAG PEVQTGRNNF VIRRNPADPQ RIPSNPSHRI QCAAGYEQSE HNVCQDIDEC TSGTHNCRTD QVCINLRGSF TCQCLPGYQK RGEQCVDIDE CTVPPYCHQR CVNTPGSFYC QCSPGFQLAA NNYTCVDINE CDASNQCAQQ CYNILGSFIC QCNQGYELSS DRLNCEDIDE CRTSSYLCQY QCVNEPGKFS CMCPQGYEVV RSRTCQDINE CETTNECRED EMCWNYHGGF RCYPRNPCQD HYVLTSENRC VCPVSNTMCR ELPQSIVYKY MSIRSDRSVP SDIFQIQATM IYANTINTFR IKSGNENGEF YLRQTSPVSA MLVLVKSLSG PREYIVDLEM LTVSSIGTFR TSSVLRLTII VGPFSFQNWP HYRSP . It is sometimes possible for the material contained within the vial of "EGF-containing fibulin-like extracellular matrix protein 1 (Efemp1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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