IgE Receptor Subunit A Recombinant Protein | FCER1A recombinant protein

Recombinant Human IgE Receptor Subunit A

Cat. Num. AAA146935

• Gene Names: FCER1A; FCE1A; FcERI
• Purity: Greater than 90.0% as determined by SDS-PAGE.
• Synonyms: IgE Receptor Subunit A; Recombinant Human IgE Receptor Subunit A; Fc Fragment Of IgE; High Affinity I; Receptor For; Alpha Polypeptide; FCE1A; IgE Fc Receptor Subunit Alpha; FcERI; Fc-Epsilon RI-Alpha; Fc Epsilon RI Alpha-Chain; Fc IgE Receptor; High Affinity Immunoglobulin Epsilon Receptor Alpha-Subunit; High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha; Immunoglobulin E Receptor; High-Affinity; Of Mast Cells; Alpha Polypeptide.; FCER1A recombinant protein

• Host: E. coli
• Purity/Purification: Greater than 90.0% as determined by SDS-PAGE.
• Form/Format: 1x PBS, pH-7.4, 50mM Arginine and 0.05% NaN₃

• Physical Appearance: Sterile filtered colorless solution (1.49mg/ml)
• Preparation and Storage: The Recombinant FCER1A protein although stable at 4°C for 1 week, should be stored below -18°C. ; For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). ; Please prevent freeze-thaw cycles.

Related Product Information for FCER1A recombinant protein

FCER1A Human Recombinant produced in E Coli is a non-glycosylated polypeptide chain containing 201 amino acids.
FCER1Ais fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.

Product Categories/Family for FCER1A recombinant protein

Recombinant & Natural Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 4503675
• NCBI GeneID: 2205
• NCBI Accession #: NP_001992.1
• NCBI GenBank Nucleotide #: NM_002001.3
• UniProt Accession #: P12319
• NCBI Official Full Name: high affinity immunoglobulin epsilon receptor subunit alpha
• NCBI Official Synonym Full Names: Fc fragment of IgE receptor Ia
• NCBI Official Symbol: FCER1A
• NCBI Official Synonym Symbols: FCE1A; FcERI
• NCBI Protein Information: high affinity immunoglobulin epsilon receptor subunit alpha
• UniProt Protein Name: High affinity immunoglobulin epsilon receptor subunit alpha
• Protein Family: High affinity immunoglobulin epsilon receptor
• UniProt Gene Name: FCER1A
• UniProt Synonym Gene Names: FCE1A; FcERI

NCBI Description

The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]

Uniprot Description

Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.